Key Genes Identified in Nonsyndromic Microtia by the Analysis of Transcriptomics and Proteomics
Sign Up to like & getrecommendations! Published in 2022 at "ACS Omega"
DOI: 10.1021/acsomega.1c07059
Abstract: As one of the common birth defects worldwide, nonsyndromic microtia is a complex disease that results from interactions between environmental and genetic factors. However, the underlying causes of nonsyndromic microtia are currently not well understood.… read more here.
Keywords: key genes; microtia; identified nonsyndromic; analysis ... See more keywords
Long-Term Clinical Results of Two-Stage Total Ear Reconstruction of Microtia Using Autologous Cell-Engineered Chondrocytes
Sign Up to like & getrecommendations! Published in 2022 at "Plastic and Reconstructive Surgery"
DOI: 10.1097/prs.0000000000009854
Abstract: Background: Microtia repair requires a large volume of reconstruction material. In pediatric patients, the collectable volume of autologous cartilage is limited, and the impact of surgical invasion and donor-site morbidity can be particularly severe. The… read more here.
Keywords: two stage; long term; microtia; reconstruction ... See more keywords
The History of Alloplastic Ear Reconstruction for Microtia
Sign Up to like & getrecommendations! Published in 2020 at "Annals of Plastic Surgery"
DOI: 10.1097/sap.0000000000002213
Abstract: Abstract Microtia reconstruction is a unique and challenging field in reconstructive surgery. In the early 20th century, many different alloplastic materials have been used in an attempt to recreate the fibrocartilaginous framework of the native… read more here.
Keywords: reconstruction; microtia; alloplastic microtia; alloplastic ear ... See more keywords
The Interchondral Joints of Thorax in Microtia Surgery: Classification and Fabrication Strategies.
Sign Up to like & getrecommendations! Published in 2021 at "Annals of Plastic Surgery"
DOI: 10.1097/sap.0000000000002582
Abstract: BACKGROUND The interchondral joint between the sixth and seventh costal cartilages, called synchondrosis, assists in harvesting and fabricating the microtia framework. However, its looseness often complicates the microtia surgery. We aimed to classify the interchondral… read more here.
Keywords: microtia; fabrication; class; microtia surgery ... See more keywords
Recommendations for the Development and Reform of Microtia and Atresia Services.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Craniofacial Surgery"
DOI: 10.1097/scs.0000000000005209
Abstract: BACKGROUND The initial step in setting up standardized microtia-atresia service is investigating the current status of the service and comparing this to internationally recognized guidelines or care standards. In many countries, documented information about microtia… read more here.
Keywords: microtia; microtia atresia; microtia service; care ... See more keywords
Decreased Tiam1‐mediated Rac1 activation is responsible for impaired directional persistence of chondrocyte migration in microtia
Sign Up to like & getrecommendations! Published in 2024 at "Journal of Cellular and Molecular Medicine"
DOI: 10.1111/jcmm.18443
Abstract: The human auricle has a complex structure, and microtia is a congenital malformation characterized by decreased size and loss of elaborate structure in the affected ear with a high incidence. Our previous studies suggest that… read more here.
Keywords: migration; directional persistence; microtia; migration microtia ... See more keywords
Effect of Cadherin-11 on the Proliferation, Migration, and ECM Synthesis of Chondrocyte
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Tissue Engineering and Regenerative Medicine"
DOI: 10.1155/2023/9985334
Abstract: Nonsyndromic microtia is a kind of congenital ear malformation with unclear pathogenic genes. Cadherin-11 (CDH11, OB-cadherin) is a member of the cadherin family, which has been demonstrated to play important roles in controlling morphogenesis and… read more here.
Keywords: effect; proliferation; chondrocyte; microtia ... See more keywords
Goldenhar syndrome with limbal neoformation, microtia and skeletal deformities: a case report and literature review
Sign Up to like & getrecommendations! Published in 2024 at "BMC Ophthalmology"
DOI: 10.1186/s12886-024-03317-9
Abstract: Background To report a case of a 4-year-old patient with Goldenhar syndrome. Case presentation The author presents a rare case report involving a 4-year-old boy with multiple malformations. A comprehensive examination showed that the patient… read more here.
Keywords: goldenhar syndrome; case report; syndrome limbal; microtia ... See more keywords
Genotype-phenotype associations in microtia: a systematic review
Sign Up to like & getrecommendations! Published in 2024 at "Orphanet Journal of Rare Diseases"
DOI: 10.1186/s13023-024-03142-9
Abstract: Background Microtia is a congenital ear malformation that can occur as isolated microtia or as part of a syndrome. The etiology is currently poorly understood, although there is strong evidence that genetics has a role… read more here.
Keywords: genotype phenotype; systematic review; microtia; microtia systematic ... See more keywords
Target sequencing of 307 deafness genes identifies candidate genes implicated in microtia.
Sign Up to like & getrecommendations! Published in 2017 at "Oncotarget"
DOI: 10.18632/oncotarget.18803
Abstract: Microtia is a congenital malformation of the external ear caused by genetic and/or environmental factors. However, no causal genetic mutations have been identified in isolated microtia patients. In this study, we utilized targeted genomic capturing… read more here.
Keywords: microtia; target sequencing; microtia patients; deafness genes ... See more keywords
JAG2: A Potential Biomarker for Microtia Identified by Integrated RNA Transcriptome Analysis
Sign Up to like & getrecommendations! Published in 2024 at "Current Genomics"
DOI: 10.2174/0113892029311725240911065539
Abstract: Introduction Microtia, a prevalent congenital maxillofacial deformity, significantly impacts the physical and psychological health of children. Its etiology, especially in non-syndromic cases, remains a complex and partially understood domain, complicating etiological treatment. Recent studies pointed… read more here.
Keywords: analysis; microtia; potential biomarker; jag2 potential ... See more keywords