Key Genes Identified in Nonsyndromic Microtia by the Analysis of Transcriptomics and Proteomics
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DOI: 10.1021/acsomega.1c07059
Abstract: As one of the common birth defects worldwide, nonsyndromic microtia is a complex disease that results from interactions between environmental and genetic factors. However, the underlying causes of nonsyndromic microtia are currently not well understood.… read more here.
Keywords: key genes; microtia; identified nonsyndromic; analysis ... See more keywords
Long-Term Clinical Results of Two-Stage Total Ear Reconstruction of Microtia Using Autologous Cell-Engineered Chondrocytes
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DOI: 10.1097/prs.0000000000009854
Abstract: Background: Microtia repair requires a large volume of reconstruction material. In pediatric patients, the collectable volume of autologous cartilage is limited, and the impact of surgical invasion and donor-site morbidity can be particularly severe. The… read more here.
Keywords: two stage; long term; microtia; reconstruction ... See more keywords
The History of Alloplastic Ear Reconstruction for Microtia
Sign Up to like & getrecommendations! Published in 2020 at "Annals of Plastic Surgery"
DOI: 10.1097/sap.0000000000002213
Abstract: Abstract Microtia reconstruction is a unique and challenging field in reconstructive surgery. In the early 20th century, many different alloplastic materials have been used in an attempt to recreate the fibrocartilaginous framework of the native… read more here.
Keywords: reconstruction; microtia; alloplastic microtia; alloplastic ear ... See more keywords
The Interchondral Joints of Thorax in Microtia Surgery: Classification and Fabrication Strategies.
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DOI: 10.1097/sap.0000000000002582
Abstract: BACKGROUND The interchondral joint between the sixth and seventh costal cartilages, called synchondrosis, assists in harvesting and fabricating the microtia framework. However, its looseness often complicates the microtia surgery. We aimed to classify the interchondral… read more here.
Keywords: microtia; fabrication; class; microtia surgery ... See more keywords
Recommendations for the Development and Reform of Microtia and Atresia Services.
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DOI: 10.1097/scs.0000000000005209
Abstract: BACKGROUND The initial step in setting up standardized microtia-atresia service is investigating the current status of the service and comparing this to internationally recognized guidelines or care standards. In many countries, documented information about microtia… read more here.
Keywords: microtia; microtia atresia; microtia service; care ... See more keywords
Effect of Cadherin-11 on the Proliferation, Migration, and ECM Synthesis of Chondrocyte
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Tissue Engineering and Regenerative Medicine"
DOI: 10.1155/2023/9985334
Abstract: Nonsyndromic microtia is a kind of congenital ear malformation with unclear pathogenic genes. Cadherin-11 (CDH11, OB-cadherin) is a member of the cadherin family, which has been demonstrated to play important roles in controlling morphogenesis and… read more here.
Keywords: effect; proliferation; chondrocyte; microtia ... See more keywords
Target sequencing of 307 deafness genes identifies candidate genes implicated in microtia.
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DOI: 10.18632/oncotarget.18803
Abstract: Microtia is a congenital malformation of the external ear caused by genetic and/or environmental factors. However, no causal genetic mutations have been identified in isolated microtia patients. In this study, we utilized targeted genomic capturing… read more here.
Keywords: microtia; target sequencing; microtia patients; deafness genes ... See more keywords
Predicting the Risk of Microtia From Prenatal Factors: A Hospital-Based Case-Control Study
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DOI: 10.3389/fped.2022.851872
Abstract: Background Although a wide range of risk factors for microtia were identified, the limitation of these studies, however, is that risk factors were not estimated in comparison with one another or from different domains. Our… read more here.
Keywords: regression; microtia; non syndromic; risk factors ... See more keywords
The psychosocial impact of microtia and ear reconstruction: A national data-linkage study
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Pediatrics"
DOI: 10.3389/fped.2023.1148975
Abstract: Introduction Children with visible facial differences are believed to be at increased risk of negative psychosocial behaviours which may manifest as affective disorders. The aim of this study was to determine whether a diagnosis of… read more here.
Keywords: diagnosis; microtia; risk; reconstruction ... See more keywords
Artificial intelligence for assessing the severity of microtia via deep convolutional neural networks
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DOI: 10.3389/fsurg.2022.929110
Abstract: Background Microtia is a congenital abnormality varying from slightly structural abnormalities to the complete absence of the external ear. However, there is no gold standard for assessing the severity of microtia. Objectives The purpose of… read more here.
Keywords: severity microtia; artificial intelligence; microtia; assessing severity ... See more keywords
Duplication in ECR near HMX1 and a SNP in GATA6 Genes Regulate Microtia in Awassi Sheep
Sign Up to like & getrecommendations! Published in 2020 at "Genes"
DOI: 10.3390/genes11060597
Abstract: Microtia and anotia are hereditary traits characterized by an underdevelopment or complete absence of the outer ear. These congenital malformations observed in many species can exist as part of various syndromes or as an isolated… read more here.
Keywords: microtia; gata6; near hmx1; ecr near ... See more keywords