Inhibition of microtubule assembly and cytotoxic effect of graphene oxide on human colorectal carcinoma cell HCT116.
Sign Up to like & getrecommendations! Published in 2021 at "Archives of biochemistry and biophysics"
DOI: 10.1016/j.abb.2021.108940
Abstract: Nanomaterials, such as graphene oxide (GO), are increasingly being investigated for their suitability in biomedical applications. Tubulin is the key molecule for the formation of microtubules crucial for cellular function and proliferation, and as such… read more here.
Keywords: graphene oxide; microtubule; colorectal carcinoma; effect ... See more keywords
Thermal hysteresis in microtubule assembly/disassembly dynamics: The aging-induced degradation of tubulin dimers
Sign Up to like & getrecommendations! Published in 2022 at "Biochemistry and Biophysics Reports"
DOI: 10.1016/j.bbrep.2021.101199
Abstract: The assembly/disassembly of biological macromolecules plays an important role in their biological functionalities. Although the dynamics of tubulin polymers and their super-assembly into microtubule structures is critical for many cellular processes, details of their cyclical… read more here.
Keywords: microtubule assembly; thermal hysteresis; tubulin; hysteresis ... See more keywords
Functional Roles of α1-, α2-, β1-, and β2-Tubulins in Vegetative Growth, Microtubule Assembly, and Sexual Reproduction of Fusarium graminearum
Sign Up to like & getrecommendations! Published in 2021 at "Applied and Environmental Microbiology"
DOI: 10.1128/aem.00967-21
Abstract: In this study, we found that F. graminearum contains four different α-/β-tubulin heterodimers (α1-β1, α1-β2, α2-β1, and α2-β2), and they assemble together into a single microtubule. Moreover, α1- and α2-tubulins are functionally interchangeable in microtubule… read more here.
Keywords: growth; microtubule; tubulin; microtubule assembly ... See more keywords