A Structural Ensemble of a Tau-Microtubule Complex Reveals Regulatory Tau Phosphorylation and Acetylation Mechanisms
Sign Up to like & getrecommendations! Published in 2021 at "ACS Central Science"
DOI: 10.1021/acscentsci.1c00585
Abstract: Tau is a microtubule-associated protein that regulates the stability of microtubules. We use metainference cryoelectron microscopy, an integrative structural biology approach, to determine an ensemble of conformations representing the structure and dynamics of a tau-microtubule… read more here.
Keywords: microtubule; tau microtubule; microtubule complex; phosphorylation acetylation ... See more keywords