Successive Kinesin-5 Microtubule Crosslinking and Sliding Promote Fast, Irreversible Formation of a Stereotyped Bipolar Spindle
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DOI: 10.1016/j.cub.2019.09.030
Abstract: Separation of duplicated spindle poles is the first step in forming the mitotic spindle. Kinesin-5 crosslinks and slides anti-parallel microtubules (MTs), but it is unclear how these two activities contribute to the first steps in… read more here.
Keywords: microtubule; bipolar spindle; fast irreversible; formation ... See more keywords
Molecular basis of the microtubule-regulating activity of microtubule crosslinking factor 1
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DOI: 10.1371/journal.pone.0182641
Abstract: The variety of microtubule arrays observed across different cell types should require a diverse group of proteins that control microtubule organization. Nevertheless, mainly because of the intrinsic propensity of microtubules to easily form bundles upon… read more here.
Keywords: microtubule; mtbd; crosslinking factor; mtcl1 ... See more keywords