Microtubule depolymerization induces ferroptosis in neuroblastoma cells
Sign Up to like & getrecommendations! Published in 2024 at "IUBMB Life"
DOI: 10.1002/iub.2899
Abstract: Estramustine (EM), a clinically successful hormone‐refractory anti‐prostate cancer drug, exhibited potent anti‐proliferative activity, depolymerized microtubules, blocked cells at mitosis, and induced cell death in different cancer cells. Altered iron metabolism is a feature of cancer… read more here.
Keywords: neuroblastoma cells; ferroptosis; microtubule depolymerization; depolymerization induces ... See more keywords
KIF2C regulates synaptic plasticity and cognition in mice through dynamic microtubule depolymerization
Sign Up to like & getrecommendations! Published in 2022 at "eLife"
DOI: 10.7554/elife.72483
Abstract: Dynamic microtubules play a critical role in cell structure and function. In nervous system, microtubules are the major route for cargo protein trafficking and they specially extend into and out of synapses to regulate synaptic… read more here.
Keywords: microtubule depolymerization; depolymerization; regulates synaptic; kif2c regulates ... See more keywords