Structure of the Ndc80 complex and its interactions at the yeast kinetochore–microtubule interface
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DOI: 10.1098/rsob.220378
Abstract: The conserved Ndc80 kinetochore complex, Ndc80c, is the principal link between spindle microtubules and centromere associated proteins during chromosome segregation. We used AlphaFold 2 to obtain structural predictions of the Ndc80 “loop” region and the… read more here.
Keywords: structure ndc80; kinetochore microtubule; microtubule interface;
The kinetochore–microtubule interface at a glance
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DOI: 10.1242/jcs.214577
Abstract: ABSTRACT Accurate chromosome segregation critically depends on the formation of attachments between microtubule polymers and each sister chromatid. The kinetochore is the macromolecular complex that assembles at the centromere of each chromosome during mitosis and… read more here.
Keywords: microtubule interface; microtubule; kinetochore microtubule; glance ... See more keywords