Dynamin‐2 regulates microtubule stability via an endocytosis‐independent mechanism
Sign Up to like & getrecommendations! Published in 2022 at "Cytoskeleton"
DOI: 10.1002/cm.21723
Abstract: Microtubule stability and dynamics regulations are essential for vital cellular processes, such as microtubule‐dependent axonal transport. Dynamin is involved in many membrane fission events, such as clathrin‐mediated endocytosis. The ubiquitously expressed dynamin‐2 has been reported… read more here.
Keywords: endocytosis; dynamin; microtubule stability; heterozygous cells ... See more keywords
Paclitaxel induces Stathmin 1 phosphorylation, microtubule stability and apoptosis in acute lymphoblastic leukemia cells
Sign Up to like & getrecommendations! Published in 2017 at "Heliyon"
DOI: 10.1016/j.heliyon.2017.e00405
Abstract: Acute lymphoblastic leukemia (ALL) is a hematological malignancy characterized by abnormal proliferation and accumulation of lymphoblasts in the hematopoietic system. Stathmin 1 is a proliferation marker for normal lymphocytes, which has been described as highly… read more here.
Keywords: microtubule stability; stathmin phosphorylation; cell; stability apoptosis ... See more keywords
Eg5 Inhibitors Have Contrasting Effects on Microtubule Stability and Metaphase Spindle Integrity.
Sign Up to like & getrecommendations! Published in 2017 at "ACS chemical biology"
DOI: 10.1021/acschembio.6b01040
Abstract: To uncover their contrasting mechanisms, antimitotic drugs that inhibit Eg5 (kinesin-5) were analyzed in mixed-motor gliding assays of kinesin-1 and Eg5 motors in which Eg5 "braking" dominates motility. Loop-5 inhibitors (monastrol, STLC, ispinesib, and filanesib)… read more here.
Keywords: microtubule stability; contrasting effects; eg5; inhibitors contrasting ... See more keywords