Wolbachia action in the sperm produces developmentally deferred chromosome segregation defects during the Drosophila mid-blastula transition
Sign Up to like & getrecommendations! Published in 2022 at "eLife"
DOI: 10.1101/2022.06.20.496611
Abstract: Wolbachia, a vertically transmitted endosymbiont infecting many insects, spreads rapidly through uninfected populations by a mechanism known as Cytoplasmic Incompatibility (CI). In CI, embryos from crosses between Wolbachia-infected males and uninfected females fail to develop… read more here.
Keywords: chromosome segregation; developmentally deferred; mid blastula; chromosome ... See more keywords
Interphase-arrested Drosophila embryos activate zygotic gene expression and initiate mid-blastula transition events at a low nuclear-cytoplasmic ratio
Sign Up to like & getrecommendations! Published in 2020 at "PLoS Biology"
DOI: 10.1371/journal.pbio.3000891
Abstract: Externally deposited eggs begin development with an immense cytoplasm and a single overwhelmed nucleus. Rapid mitotic cycles restore normality as the ratio of nuclei to cytoplasm (N/C) increases. A threshold N/C has been widely proposed… read more here.
Keywords: cyclin cdk1; drosophila embryos; ratio; blastula transition ... See more keywords
MiR-202-3p determines embryo viability during mid-blastula transition
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2022.897826
Abstract: Developmental growth is an intricate process involving the coordinated regulation of the expression of various genes, and microRNAs (miRNAs) play crucial roles in diverse processes throughout animal development. The mid-blastula transition (MBT) is a developmental… read more here.
Keywords: blastula transition; mir 202; blastula; mid blastula ... See more keywords
Temporal Gradients Controlling Embryonic Cell Cycle
Sign Up to like & getrecommendations! Published in 2021 at "Biology"
DOI: 10.3390/biology10060513
Abstract: Simple Summary Embryonic cells sense temporal gradients of regulatory signals to determine whether and when to proceed or remodel the cell cycle. Such a control mechanism is allowed to accurately link the cell cycle with… read more here.
Keywords: temporal gradients; embryonic cell; cell cycle; mid blastula ... See more keywords