Transcriptomic analysis and fusion gene identifications of midbody remnants released from colorectal cancer cells reveals they are molecularly distinct from exosomes and microparticles
Sign Up to like & getrecommendations! Published in 2024 at "PROTEOMICS"
DOI: 10.1002/pmic.202300058
Abstract: Previously, we reported that human primary (SW480) and metastatic (SW620) colorectal (CRC) cells release three classes of membrane‐encapsulated extracellular vesicles (EVs); midbody remnants (MBRs), exosomes (Exos), and microparticles (MPs). We reported that MBRs were molecularly… read more here.
Keywords: cancer; fusion; analysis; fusion gene ... See more keywords
The viral restriction factor tetherin/BST2 tethers cytokinetic midbody remnants to the cell surface
Sign Up to like & getrecommendations! Published in 2021 at "Current Biology"
DOI: 10.1016/j.cub.2021.02.039
Abstract: The midbody at the center of the intercellular bridge connecting dividing cells recruits the machinery essential for the final steps of cytokinesis.1-5 Successive abscission on both sides of the midbody generates a free midbody remnant… read more here.
Keywords: cell surface; bst2; midbody; midbody remnants ... See more keywords