Basal constriction during midbrain–hindbrain boundary morphogenesis is mediated by Wnt5b and focal adhesion kinase
Sign Up to like & getrecommendations! Published in 2018 at "Biology Open"
DOI: 10.1242/bio.034520
Abstract: ABSTRACT Basal constriction occurs at the zebrafish midbrain–hindbrain boundary constriction (MHBC) and is likely a widespread morphogenetic mechanism. 3D reconstruction demonstrates that MHBC cells are wedge-shaped, and initially constrict basally, with subsequent apical expansion. wnt5b… read more here.
Keywords: focal adhesion; constriction; midbrain hindbrain; hindbrain boundary ... See more keywords
Genome-wide 5-hydroxymethylcytosine (5hmC) reassigned in Pten-depleted mESCs along neural differentiation
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2022.956604
Abstract: DNA methylation and hydroxymethylation have been implicated in the regulatory dynamics of gene expression in normal development and differentiation. 5-Hydroxymethylcytosine (5hmC), created by the ten-eleven translocation (TET) protein-catalyzed oxidation of 5-methylcytosine (5mC), is abundant in… read more here.
Keywords: differentiation; genome wide; midbrain hindbrain; hydroxymethylcytosine 5hmc ... See more keywords