Mechanistic Middle-Out Physiologically Based Toxicokinetic Modeling of Transporter-Dependent Disposition of Perfluorooctanoic Acid in Humans
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DOI: 10.1021/acs.est.2c05642
Abstract: Perfluorooctanoic acid (PFOA) is an environmental toxicant exhibiting a years-long biological half-life (t1/2) in humans and is linked with adverse health effects. However, limited understanding of its toxicokinetics (TK) has obstructed the necessary risk assessment.… read more here.
Keywords: middle physiologically; transporter; based toxicokinetic; physiologically based ... See more keywords