Targeting Mast Cell Activation and MIF-Mediated Remodelling Enhances Chemotherapy Response in Pancreatic Cancer.
Sign Up to like & getrecommendations! Published in 2025 at "Advanced science"
DOI: 10.1002/advs.202509930
Abstract: Neoadjuvant gemcitabine plus nab‐paclitaxel (AG) is increasingly applied in pancreatic ductal adenocarcinoma (PDAC), yet its effects on the tumor microenvironment (TME) remain incompletely defined. By integrating eight single‐cell RNA sequencing datasets and nine multicenter transcriptomic… read more here.
Keywords: targeting mast; mif; cancer; mast cell ... See more keywords
MIF is essential to the establishment of house dust mite-induced airway inflammation and tissue remodeling in mice.
Sign Up to like & getrecommendations! Published in 2023 at "European journal of immunology"
DOI: 10.1002/eji.202250016
Abstract: Macrophage migration inhibitory factor (MIF) is present in high amounts in the bronchoalveolar lavage fluid (BALF) and serum of asthmatic patients contributing to the pathogenesis of experimental asthma induced by ovalbumin (OVA) in mice. Whether… read more here.
Keywords: hdm challenged; house dust; mif; mice ... See more keywords
The VEGF‐Mediated Cytoprotective Ability of MIF‐Licensed Mesenchymal Stromal Cells in House Dust Mite‐Induced Epithelial Damage
Sign Up to like & getrecommendations! Published in 2024 at "European Journal of Immunology"
DOI: 10.1002/eji.202451205
Abstract: Enhancing mesenchymal stromal cell (MSC) therapeutic efficacy through licensing with proinflammatory cytokines is now well established. We have previously shown that macrophage migration inhibitory factor (MIF)‐licensed MSCs exerted significantly enhanced therapeutic efficacy in reducing inflammation… read more here.
Keywords: house dust; mif; mesenchymal stromal; dust mite ... See more keywords
Macrophage migration inhibitory factor gene polymorphisms (SNP -173 G>C and STR-794 CATT5-8) confer risk of plaque psoriasis: A case-control study.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of clinical laboratory analysis"
DOI: 10.1002/jcla.23999
Abstract: BACKGROUND Macrophage inhibitory factor (MIF) is a pro-inflammatory cytokine secreted by several cells, including those in the immune system and the skin. The MIF gene contains the SNP -173 G> C and STR -794 CATT5-8… read more here.
Keywords: snp 173; risk; inhibitory factor; mif ... See more keywords
Macrophage migration inhibitory factor regulates specific innate immune sensor responses in gingival epithelial cells.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of periodontology"
DOI: 10.1002/jper.21-0598
Abstract: BACKGROUND The gingival epithelium protects periodontal tissues and the alveolar bone by maintaining a steady state of regulated inflammatory surveillance, also known as healthy homeostasis. Accordingly, the repertoire of receptors present within the gingival epithelium… read more here.
Keywords: migration inhibitory; inhibitory factor; macrophage migration; mif ... See more keywords
Macrophage inhibitory factor (MIF) gene polymorphisms are associated with disease susceptibility and with circulating MIF levels in active non‐segmental vitiligo in patients from western Mexico
Sign Up to like & getrecommendations! Published in 2020 at "Molecular Genetics & Genomic Medicine"
DOI: 10.1002/mgg3.1416
Abstract: The macrophage migration inhibiting factor (MIF) is a protein that promotes the activation of immune cells and the production of other proinflammatory cytokines such as TNF‐α, IL‐1β, and IFN‐γ, which have proposed to play an… read more here.
Keywords: non segmental; vitiligo; factor mif; western mexico ... See more keywords
The clinical signature of genetic variants and serum levels of macrophage migration inhibitory factor in Egyptian breast cancer patients
Sign Up to like & getrecommendations! Published in 2024 at "Breast Cancer Research and Treatment"
DOI: 10.1007/s10549-024-07393-9
Abstract: Macrophage migration inhibitory factor (MIF) is an integral cytokine for the modulation of both innate and adaptive immunity and is involved in the pathogenesis of various cancers. However, conflicting findings on the relationship between MIF… read more here.
Keywords: serum; mif; breast cancer; serum mif ... See more keywords
Expression profile of macrophage migration inhibitory factor in periodontitis.
Sign Up to like & getrecommendations! Published in 2020 at "Archives of oral biology"
DOI: 10.1016/j.archoralbio.2020.105003
Abstract: OBJECTIVE Macrophage migration inhibitory factor (MIF) is a pivotal mediator of host innate immunity and influences the development of several inflammatory diseases. The role of MIF in periodontitis is unclear. METHODS Eighteen periodontally healthy volunteers… read more here.
Keywords: macrophage migration; inhibitory factor; tissue; migration inhibitory ... See more keywords
LncRNA MEG3 inhibits the proliferation of neural stem cells after ischemic stroke via the miR-493-5P/MIF axis.
Sign Up to like & getrecommendations! Published in 2021 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2021.06.033
Abstract: OBJECTIVE The proliferation of neural stem cells (NSCs1), or lack thereof, can have profound effects on brain tissue remodeling for ischemic stroke (IS2). In this study, we aimed to reveal the influence of the lncRNA… read more here.
Keywords: nsc proliferation; proliferation; mif; mir 493 ... See more keywords
The N-terminus of MIF Regulates the Dynamic Profile of Residues Involved in CD74 Activation.
Sign Up to like & getrecommendations! Published in 2021 at "Biophysical journal"
DOI: 10.1016/j.bpj.2021.08.025
Abstract: Macrophage migration inhibitory factor (MIF) is an immunomodulatory protein with a pathogenic activity in various inflammatory disorders, autoimmune diseases, and cancer. The majority of MIF-triggered pathological conditions are associated with activation of the cell surface… read more here.
Keywords: cd74 activation; mif; terminus mif; activation ... See more keywords
Evolving complexity of MIF signaling.
Sign Up to like & getrecommendations! Published in 2019 at "Cellular signalling"
DOI: 10.1016/j.cellsig.2019.01.006
Abstract: Macrophage migration inhibitory factor (MIF) is a cytokine expressed in various cell types, including hematopoietic, epithelial, endothelial, mesenchymal and neuronal cells. Altered MIF expression has been associated with a multitude of diseases ranging from inflammatory… read more here.
Keywords: signaling pathways; evolving complexity; complexity mif; mif ... See more keywords