Mifepristone Access Through Community Pharmacies When Regulated as a Routine Prescription Medication
Sign Up to like & getrecommendations! Published in 2025 at "JAMA Network Open"
DOI: 10.1001/jamanetworkopen.2025.42096
Abstract: This cross-sectional study quantifies the availability of mifepristone within 3 calendar days at community pharmacies across British Columbia, Canada. read more here.
Keywords: access community; pharmacies regulated; mifepristone access; community pharmacies ... See more keywords
Dosing interval between mifepristone and misoprostol in second and third trimester termination
Sign Up to like & getrecommendations! Published in 2018 at "Archives of Gynecology and Obstetrics"
DOI: 10.1007/s00404-018-5017-9
Abstract: ObjectiveTo compare several strategies for second trimester labor induction for termination of pregnancy (TOP) using misoprostol and mifepristone and to determine which one is more effective in accelerating the time to delivery.MethodThis was a retrospective… read more here.
Keywords: second third; mifepristone; third trimester; day ... See more keywords
Effects of Ketoconazole on the Pharmacokinetics of Mifepristone, a Competitive Glucocorticoid Receptor Antagonist, in Healthy Men
Sign Up to like & getrecommendations! Published in 2017 at "Advances in Therapy"
DOI: 10.1007/s12325-017-0621-9
Abstract: IntroductionMifepristone, a competitive glucocorticoid receptor antagonist approved for Cushing syndrome, and ketoconazole, an antifungal and steroidogenesis inhibitor, are both inhibitors of and substrates for cytochrome P450 (CYP3A4). This study evaluated the pharmacokinetic effects of concomitant… read more here.
Keywords: receptor antagonist; mifepristone; exposure; period ... See more keywords
A cross-sectional analysis of mifepristone, misoprostol, and combination mifepristone-misoprostol package inserts obtained in 20 countries.
Sign Up to like & getrecommendations! Published in 2020 at "Contraception"
DOI: 10.1016/j.contraception.2020.01.011
Abstract: OBJECTIVES To evaluate the characteristics, clinical information, and storage instructions contained in package inserts from medical abortion commodities collected in low- and middle-income countries. STUDY DESIGN From November 2017 to February 2018 mifepristone, misoprostol, and… read more here.
Keywords: mifepristone misoprostol; mifepristone; medical abortion; package inserts ... See more keywords
Mifepristone followed by misoprostol compared with placebo followed by misoprostol as medical treatment for early pregnancy loss (the Triple M trial): A double-blind placebo-controlled randomised trial
Sign Up to like & getrecommendations! Published in 2021 at "EClinicalMedicine"
DOI: 10.1016/j.eclinm.2020.100716
Abstract: Background Worldwide, millions of women seek treatment for early pregnancy loss (EPL) annually. Medical management with misoprostol is widely used, but only effective 60% of the time. Pre-treatment with mifepristone prior to misoprostol might improve… read more here.
Keywords: trial; mifepristone; treatment; followed misoprostol ... See more keywords
Cognitive effects of mifepristone in overweight, euthymic adults with depressive disorders.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of affective disorders"
DOI: 10.1016/j.jad.2018.07.014
Abstract: BACKGROUND Previous studies have shown that individuals with mood disorders have a higher prevalence of both hypercortisolemia and insulin resistance. Insulin resistance is posited to contribute to the cognitive deficits observed in individuals who have… read more here.
Keywords: depressive disorders; mifepristone; treatment; disorders cognitive ... See more keywords
Mifepristone-Misoprostol Use for Second and Third Trimester Medical Termination of Pregnancy in a Canadian Tertiary Care Centre.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of obstetrics and gynaecology Canada : JOGC = Journal d'obstetrique et gynecologie du Canada : JOGC"
DOI: 10.1016/j.jogc.2021.12.010
Abstract: OBJECTIVE This study aims to evaluate the impact of the implementation a mifepristone-misoprostol protocol (MIFE/MISO) on the induction-to-expulsion interval in the context of second- and third-trimester pregnancy termination or intrauterine fetal death (IUFD) compared with… read more here.
Keywords: mifepristone; group; second third; miso group ... See more keywords
Mifepristone regulates macrophage-mediated natural killer cells function in decidua.
Sign Up to like & getrecommendations! Published in 2021 at "Reproductive biology"
DOI: 10.1016/j.repbio.2021.100541
Abstract: Mifepristone has been used for first-trimester abortion and contraception. Nevertheless, its functional mechanism still needs to be elucidated. Decidua tissues were collected from 40 pregnant women who received (20 patients) or did not receive (20… read more here.
Keywords: mifepristone; mifepristone regulates; macrophage mediated; tgf ... See more keywords
Study of effects of mifepristone on full-term pregnancies
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Obstetrics and Gynaecology"
DOI: 10.1080/01443615.2019.1606184
Abstract: Abstract The induction of labour is required for various indications in obstetrics. Various regimens and drugs are advocated for use in labour induction. Mifepristone is one such drug which has a definite role in first… read more here.
Keywords: term pregnancies; term; mifepristone; obstetrics ... See more keywords
Mifepristone and rapamycin have non-additive benefits for life span in mated female Drosophila
Sign Up to like & getrecommendations! Published in 2024 at "Fly"
DOI: 10.1080/19336934.2024.2419151
Abstract: ABSTRACT The drugs mifepristone and rapamycin were compared for their relative ability to increase the life span of mated female Drosophila melanogaster. Titration of rapamycin indicated an optimal concentration of approximately 50 μM, which increased median… read more here.
Keywords: mated female; mifepristone rapamycin; mifepristone; life span ... See more keywords
The use of mifepristone in abortion associated with an increased risk of uterine leiomyomas
Sign Up to like & getrecommendations! Published in 2017 at "Medicine"
DOI: 10.1097/md.0000000000006680
Abstract: Abstract To investigate the association between widespread use of mifepristone in abortions and risk of uterine leiomyomas. We conducted a case-control study of 305 patients with uterine leiomyomas between January 2011 and July 2012; 311… read more here.
Keywords: abortion; uterine leiomyomas; risk; mifepristone ... See more keywords