Bleb Expansion in Migrating Cells Depends on Supply of Membrane from Cell Surface Invaginations.
Sign Up to like & getrecommendations! Published in 2017 at "Developmental cell"
DOI: 10.1016/j.devcel.2017.10.030
Abstract: Cell migration is essential for morphogenesis, organ formation, and homeostasis, with relevance for clinical conditions. The migration of primordial germ cells (PGCs) is a useful model for studying this process in the context of the… read more here.
Keywords: bleb expansion; formation; migrating cells; cell ... See more keywords
In Situ Single-Molecule Imaging of MicroRNAs in Switchable Migrating Cells under Biomimetic Confinement.
Sign Up to like & getrecommendations! Published in 2022 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.1c05223
Abstract: Spatial imaging of RNAs in single cells is extremely charming for deciphering of regulatory mechanisms in multiple migration modes during tumor metastasis. Herein, enzyme-free-mediated cascade amplified nanoprobes were designed for in situ single-molecule imaging of… read more here.
Keywords: migrating cells; situ single; single molecule; switchable migrating ... See more keywords
Chemokine-biased robust self-organizing polarization of migrating cells in vivo
Sign Up to like & getrecommendations! Published in 2021 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2018480118
Abstract: Significance Bleb-driven cell migration plays important roles in diverse biological processes. Here, we present the mechanism for polarity establishment and maintenance in blebbing cells in vivo. We show that actin polymerization defines the leading edge,… read more here.
Keywords: cells vivo; polarization; cell front; polarity ... See more keywords
Using migrating cells as probes to illuminate features in live embryonic tissues
Sign Up to like & getrecommendations! Published in 2020 at "Science Advances"
DOI: 10.1126/sciadv.abc5546
Abstract: Migrating cells can serve as probes for determining tissue properties in live embryos. The biophysical and biochemical properties of live tissues are important in the context of development and disease. Methods for evaluating these properties… read more here.
Keywords: probes illuminate; cells probes; tissue; migrating cells ... See more keywords