Evaluation of the relationship between macrophage migration inhibitory factor level and clinical course in patients with COVID‐19 pneumonia
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Medical Virology"
DOI: 10.1002/jmv.27189
Abstract: The COVID‐19 pandemic, which has ravaged our world for more than a year, still shapes our agenda with a scale of intensity that fluctuates over time. In our study, we aimed to determine the correlation… read more here.
Keywords: migration inhibitory; mif level; inhibitory factor; level ... See more keywords
Macrophage migration inhibitory factor regulates specific innate immune sensor responses in gingival epithelial cells.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of periodontology"
DOI: 10.1002/jper.21-0598
Abstract: BACKGROUND The gingival epithelium protects periodontal tissues and the alveolar bone by maintaining a steady state of regulated inflammatory surveillance, also known as healthy homeostasis. Accordingly, the repertoire of receptors present within the gingival epithelium… read more here.
Keywords: migration inhibitory; inhibitory factor; macrophage migration; mif ... See more keywords
The regulation of protein kinase casein kinase II by apigenin is involved in the inhibition of ultraviolet B‐induced macrophage migration inhibitory factor‐mediated hyperpigmentation
Sign Up to like & getrecommendations! Published in 2019 at "Phytotherapy Research"
DOI: 10.1002/ptr.6597
Abstract: Ultraviolet (UV) radiation elicits melanogenesis and pigmentation in the skin. Apigenin (4′,5,7‐trihydroxyflavone [AGN]) is a plant flavone contained in various herbs, fruits, and vegetables. We herein investigated antimelanogenic properties of AGN and the molecular mechanisms… read more here.
Keywords: macrophage migration; inhibitory factor; hyperpigmentation; migration inhibitory ... See more keywords
Expression profile of macrophage migration inhibitory factor in periodontitis.
Sign Up to like & getrecommendations! Published in 2020 at "Archives of oral biology"
DOI: 10.1016/j.archoralbio.2020.105003
Abstract: OBJECTIVE Macrophage migration inhibitory factor (MIF) is a pivotal mediator of host innate immunity and influences the development of several inflammatory diseases. The role of MIF in periodontitis is unclear. METHODS Eighteen periodontally healthy volunteers… read more here.
Keywords: macrophage migration; inhibitory factor; tissue; migration inhibitory ... See more keywords
Epigenetic regulation in macrophage migration inhibitory factor (MIF)-mediated signaling in cancer and inflammation.
Sign Up to like & getrecommendations! Published in 2021 at "Drug discovery today"
DOI: 10.1016/j.drudis.2021.03.012
Abstract: Epigenetic mechanisms are important for the regular development and maintenance of the tissue-specific expression of cytokine genes. One of the crucial cytokines involved in cancer and inflammation is macrophage migration inhibitory factor (MIF), which triggers… read more here.
Keywords: macrophage migration; cancer inflammation; migration inhibitory; mif ... See more keywords
Macrophage migration inhibitory factor (MIF) is associated with degree of collateralization in patients with totally occluded coronary arteries.
Sign Up to like & getrecommendations! Published in 2018 at "International journal of cardiology"
DOI: 10.1016/j.ijcard.2018.03.094
Abstract: BACKGROUND Collaterals in patients with coronary artery disease (CAD) limit myocardial infarction and improve survival. Macrophage migration inhibitory factor (MIF) might play a role in collateral development. We aimed this study to evaluate the association… read more here.
Keywords: macrophage migration; inhibitory factor; factor mif; migration inhibitory ... See more keywords
Pathogenic contribution of the Macrophage migration inhibitory factor family to major depressive disorder and emerging tailored therapeutic approaches.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of affective disorders"
DOI: 10.1016/j.jad.2019.11.127
Abstract: BACKGROUND Immunoinflammatory disorders are often accompanied by depression. Here, we review the available preclinical and clinical studies suggesting a role for the pro-inflammatory cytokine Macrophage migration inhibitory factor (MIF) and the second member of the… read more here.
Keywords: macrophage migration; inhibitory factor; major depressive; migration inhibitory ... See more keywords
Increased serum levels and promoter polymorphisms of macrophage migration inhibitory factor in schizophrenia
Sign Up to like & getrecommendations! Published in 2018 at "Progress in Neuro-Psychopharmacology and Biological Psychiatry"
DOI: 10.1016/j.pnpbp.2018.01.001
Abstract: Background: Numerous studies have suggested that an immune system imbalance plays an important role in schizophrenia. Macrophage migration inhibitory factor (MIF) is a pleiotropic cytokine. It plays multiple roles in various biological processes, including inflammation… read more here.
Keywords: macrophage migration; schizophrenia; inhibitory factor; migration inhibitory ... See more keywords
Redox-dependent structure and dynamics of macrophage migration inhibitory factor reveal sites of latent allostery.
Sign Up to like & getrecommendations! Published in 2022 at "Structure"
DOI: 10.1016/j.str.2022.03.007
Abstract: Macrophage migration inhibitory factor (MIF) is a multifunctional immunoregulatory protein that is a key player in the innate immune response. Given its overexpression at sites of inflammation and in diseases marked by increasingly oxidative environments,… read more here.
Keywords: redox dependent; redox; macrophage migration; inhibitory factor ... See more keywords
Design, Synthesis, and Biological Activity of New N-(Phenylmethyl)-benzoxazol-2-thiones as Macrophage Migration Inhibitory Factor (MIF) Antagonists: Efficacies in Experimental Pulmonary Hypertension.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of medicinal chemistry"
DOI: 10.1021/acs.jmedchem.7b01312
Abstract: Macrophage migration inhibitory factor (MIF) is a key pleiotropic mediator and a promising therapeutic target in cancer as well as in several inflammatory and cardiovascular diseases including pulmonary arterial hypertension (PAH). Here, a novel series… read more here.
Keywords: macrophage migration; inhibitory factor; factor mif; migration inhibitory ... See more keywords
Adding a Hydrogen Bond May Not Help: Naphthyridinone vs Quinoline Inhibitors of Macrophage Migration Inhibitory Factor.
Sign Up to like & getrecommendations! Published in 2017 at "ACS medicinal chemistry letters"
DOI: 10.1021/acsmedchemlett.7b00384
Abstract: Coordination of the ammonium group of Lys32 in the active site of human macrophage migration inhibitory factor (MIF) using a 1,7-naphthyridin-8-one instead of a quinoline is investigated. Both gas- and aqueous-phase DFT calculations for model… read more here.
Keywords: macrophage migration; inhibitory factor; hydrogen; hydrogen bond ... See more keywords