Glutaredoxin 2 promotes SP-1-dependent CSPG4 transcription and migration of wound healing NG2 glia and glioma cells: Enzymatic Taoism.
Sign Up to like & getrecommendations! Published in 2021 at "Redox biology"
DOI: 10.1016/j.redox.2021.102221
Abstract: Redox regulation of specific cysteines via oxidoreductases of the thioredoxin family is increasingly being recognized as an important signaling pathway. Here, we demonstrate that the cytosolic isoform of the vertebrate-specific oxidoreductase Glutaredoxin 2 (Grx2c) regulates… read more here.
Keywords: migration wound; enzymatic taoism; transcription; wound healing ... See more keywords
Spatiotemporal H2O2 flashes coordinate actin cytoskeletal remodeling and regulate cell migration and wound healing
Sign Up to like & getrecommendations! Published in 2025 at "Nature Communications"
DOI: 10.1038/s41467-025-62272-1
Abstract: Well-organized repair of damaged barrier epithelia is vital for infection control, resolution of inflammation, and enduring physical protection. Cysteine thiol and methionine oxidation are connected to cytoskeletal rearrangements in cell migration and wound healing, but… read more here.
Keywords: duox2; h2o2; migration; cell migration ... See more keywords