PABPN1L assemble into "ring-like" aggregates in the cytoplasm of MII oocytes and is associated with female infertility†.
Sign Up to like & getrecommendations! Published in 2021 at "Biology of reproduction"
DOI: 10.1093/biolre/ioab203
Abstract: Infertility affects 10% - 15% of families worldwide. However, the pathogenesis of female infertility caused by abnormal early embryonic development is not clear. A resent study showed that PABPN1L recruited BTG4 to mRNA 3'-poly(A) tails… read more here.
Keywords: pabpn1l; female infertility; ring like; mii oocytes ... See more keywords
O-170 Predictive value of cytoplasmic granulation patterns during IVF in MII oocytes from young donors
Sign Up to like & getrecommendations! Published in 2021 at "Human Reproduction"
DOI: 10.1093/humrep/deab127.051
Abstract: Do ooplasm granulation patterns of donor MII oocytes have similar predictive values for in vitro fertilization (IVF) outcomes as they have in older infertile women? Ooplasm granulation patterns of donor MII oocytes are predictive for… read more here.
Keywords: ooplasm granulation; granulation; mii oocytes; granulation patterns ... See more keywords
O-171 Altered meiotic spindle morphology and composition in in vitro matured oocytes
Sign Up to like & getrecommendations! Published in 2021 at "Human Reproduction"
DOI: 10.1093/humrep/deab127.052
Abstract: How does the meiotic spindle tubulin PTMs of MII oocytes matured in vitro compare to that of MII oocytes matured in vivo? MII cultured in vitro present detyrosinated tubulin in the spindle microtubules, while MII… read more here.
Keywords: vivo matured; mii; spindle; mii oocytes ... See more keywords
O-186 A novel micro-insemination method, assisted sperm fusion insemination, increases the embryo utilization rate compared to conventional intracytoplasmic sperm injection
Sign Up to like & getrecommendations! Published in 2024 at "Human Reproduction"
DOI: 10.1093/humrep/deae108.219
Abstract: Does a novel micro-insemination method, assisted sperm fusion insemination (ASFI), improve fertilization and embryonic development compared to conventional intracytoplasmic sperm injection (C-ICSI)? ASFI showed comparable fertilization and blastocyst formation rates to C-ICSI, while achieving significantly… read more here.
Keywords: insemination; rate; fertilization; mii oocytes ... See more keywords
P-294 Non-invasive classification of human oocytes using AI-powered METAPHOR metabolic imaging
Sign Up to like & getrecommendations! Published in 2025 at "Human Reproduction"
DOI: 10.1093/humrep/deaf097.602
Abstract: Can we classify human oocytes non-invasively using METAPHOR based on their metabolic hyperspectral (HS) signature and mitochondrial content? METAPHOR provides a tool to determine the physiology of human oocytes non-invasively based on their metabolism and… read more here.
Keywords: physiology; human oocytes; metaphor; metabolism ... See more keywords
In vitro Culture of Early Secondary Preantral Follicles to Obtain MII Oocyte Developmental Competence from CD-1 Outbred Mice
Sign Up to like & getrecommendations! Published in 2020 at "Indian Journal of Animal Research"
DOI: 10.18805/ijar.b-1247
Abstract: Background: The ovarian follicle is the fundamental functional tissue unit that consists of mammalian ovary. In humans, it has been known that females are born with a maximum number of follicles or oocytes that are… read more here.
Keywords: vitro culture; secondary follicles; mii oocytes; culture early ... See more keywords
Effects of MICU1-Mediated Mitochondrial Calcium Uptake on Energy Metabolism and Quality of Vitrified-Thawed Mouse Metaphase II Oocytes
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23158629
Abstract: Background: Oocyte vitrification has been widely used in the treatment of infertility and fertility preservation. However, vitrification-induced mitochondrial damage adversely affects oocyte development. Several studies have reported that mitochondrial calcium uptake protein 1 (MICU1) regulates… read more here.
Keywords: calcium; vitrification; micu1; calcium uptake ... See more keywords