PABPN1L assemble into "ring-like" aggregates in the cytoplasm of MII oocytes and is associated with female infertility†.
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DOI: 10.1093/biolre/ioab203
Abstract: Infertility affects 10% - 15% of families worldwide. However, the pathogenesis of female infertility caused by abnormal early embryonic development is not clear. A resent study showed that PABPN1L recruited BTG4 to mRNA 3'-poly(A) tails… read more here.
Keywords: pabpn1l; female infertility; ring like; mii oocytes ... See more keywords
O-170 Predictive value of cytoplasmic granulation patterns during IVF in MII oocytes from young donors
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DOI: 10.1093/humrep/deab127.051
Abstract: Do ooplasm granulation patterns of donor MII oocytes have similar predictive values for in vitro fertilization (IVF) outcomes as they have in older infertile women? Ooplasm granulation patterns of donor MII oocytes are predictive for… read more here.
Keywords: ooplasm granulation; granulation; mii oocytes; granulation patterns ... See more keywords
O-171 Altered meiotic spindle morphology and composition in in vitro matured oocytes
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DOI: 10.1093/humrep/deab127.052
Abstract: How does the meiotic spindle tubulin PTMs of MII oocytes matured in vitro compare to that of MII oocytes matured in vivo? MII cultured in vitro present detyrosinated tubulin in the spindle microtubules, while MII… read more here.
Keywords: vivo matured; mii; spindle; mii oocytes ... See more keywords
In vitro Culture of Early Secondary Preantral Follicles to Obtain MII Oocyte Developmental Competence from CD-1 Outbred Mice
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DOI: 10.18805/ijar.b-1247
Abstract: Background: The ovarian follicle is the fundamental functional tissue unit that consists of mammalian ovary. In humans, it has been known that females are born with a maximum number of follicles or oocytes that are… read more here.
Keywords: vitro culture; secondary follicles; mii oocytes; culture early ... See more keywords
Effects of MICU1-Mediated Mitochondrial Calcium Uptake on Energy Metabolism and Quality of Vitrified-Thawed Mouse Metaphase II Oocytes
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DOI: 10.3390/ijms23158629
Abstract: Background: Oocyte vitrification has been widely used in the treatment of infertility and fertility preservation. However, vitrification-induced mitochondrial damage adversely affects oocyte development. Several studies have reported that mitochondrial calcium uptake protein 1 (MICU1) regulates… read more here.
Keywords: calcium; vitrification; micu1; calcium uptake ... See more keywords