Articles with "milbemycin oxime" as a keyword



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Efficacy of afoxolaner plus milbemycin oxime chewable tablets (NexGard Spectra®, Merial) against adult Ancylostoma ceylanicum hookworm, in dogs.

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Published in 2017 at "Veterinary parasitology"

DOI: 10.1016/j.vetpar.2017.03.028

Abstract: A fixed-combination chewable tablet incorporating afoxolaner plus milbemycin oxime (NexGard Spectra®, Merial) was tested in purpose-bred Beagle dogs for efficacy against adult Ancylostoma ceylanicum hookworms. Sixteen dogs were inoculated each by oral administration of approximately… read more here.

Keywords: ceylanicum; milbemycin oxime; plus milbemycin; chewable tablets ... See more keywords
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The intravenous and oral pharmacokinetics of afoxolaner and milbemycin oxime when used as a combination chewable parasiticide for dogs

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Published in 2017 at "Journal of Veterinary Pharmacology and Therapeutics"

DOI: 10.1111/jvp.12332

Abstract: The pharmacokinetics of afoxolaner and milbemycin oxime (A3 and A4 forms) in dogs were evaluated following the oral administration of NexGard Spectra® (Merial), a fixed combination chewable formulation of these two active pharmaceutical ingredients. Absorption… read more here.

Keywords: afoxolaner milbemycin; combination; milbemycin oxime;

Safety of oral afoxolaner formulated with or without milbemycin oxime in homozygous MDR1‐deficient collie dogs

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Published in 2022 at "Journal of Veterinary Pharmacology and Therapeutics"

DOI: 10.1111/jvp.13064

Abstract: Abstract Afoxolaner, an insecticide and acaricide compound of the isoxazoline class, is available for dogs as an oral ectoparasiticide medicine (NexGard®) and as an oral endectoparasiticide medicine in combination with milbemycin oxime (MO), a macrocyclic… read more here.

Keywords: safety; homozygous mdr1; collie dogs; afoxolaner ... See more keywords