Chronic mild hypoxia increases expression of laminins 111 and 411 and the laminin receptor α6β1 integrin at the blood-brain barrier
Sign Up to like & getrecommendations! Published in 2018 at "Brain Research"
DOI: 10.1016/j.brainres.2018.07.012
Abstract: The laminin family of glycoproteins are major constituents of the basal lamina of blood vessels, and play a fundamental role in promoting endothelial differentiation and blood-brain barrier (BBB) stability. Chronic mild hypoxia (CMH), in which… read more here.
Keywords: mild hypoxia; expression laminins; expression; blood ... See more keywords
A nitroreductase-activatable near-infrared theranostic photosensitizer for photodynamic therapy under mild hypoxia.
Sign Up to like & getrecommendations! Published in 2020 at "Chemical communications"
DOI: 10.1039/d0cc02019b
Abstract: In this study, a near-infrared (NIR) theranostic photosensitizer was developed based on a heptamethine aminocyanine dye with a long-lived triplet state. This theranostic molecule can be activated by nitroreductase under mild hypoxia to be used… read more here.
Keywords: near infrared; photodynamic therapy; mild hypoxia; theranostic photosensitizer ... See more keywords
Both maternal and embryonic exposure to mild hypoxia influence embryonic development of the intertidal gastropod Littorina littorea
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Experimental Biology"
DOI: 10.1242/jeb.221895
Abstract: ABSTRACT There is growing evidence that maternal exposure to environmental stressors can alter offspring phenotype and increase fitness. Here, we investigate the relative and combined effects of maternal and developmental exposure to mild hypoxia (65… read more here.
Keywords: exposure mild; embryonic exposure; mild hypoxia; exposure ... See more keywords
Four weeks of high‐intensity training in moderate, but not mild hypoxia improves performance and running economy more than normoxic training in horses
Sign Up to like & getrecommendations! Published in 2021 at "Physiological Reports"
DOI: 10.14814/phy2.14760
Abstract: We investigated whether horses trained in moderate and mild hypoxia demonstrate greater improvement in performance and aerobic capacity compared to horses trained in normoxia and whether the acquired training effects are maintained after 2 weeks… read more here.
Keywords: mild; moderate mild; mild hypoxia; training ... See more keywords
Mild hypoxia and human bone marrow mesenchymal stem cells synergistically enhance expansion and homing capacity of human cord blood CD34+ stem cells
Sign Up to like & getrecommendations! Published in 2018 at "Iranian Journal of Basic Medical Sciences"
DOI: 10.22038/ijbms.2018.26820.6561
Abstract: Objective(s): Cord blood (CB) is known as a valuable source of hematopoietic stem cells (HSC). Identifying strategies that enhance expansion and maintain engraftment and homing capacity of HSCs can improve transplant efficiency. In this study,… read more here.
Keywords: expansion; mild hypoxia; homing capacity; stem cells ... See more keywords
Hemoglobin Oxygen Saturation with Mild Hypoxia and Microgravity.
Sign Up to like & getrecommendations! Published in 2017 at "Aerospace medicine and human performance"
DOI: 10.3357/amhp.4804.2017
Abstract: INTRODUCTION Microgravity (μG) exposure and even early recovery from μG in combination with mild hypoxia may increase the alveolar-arterial oxygen (O2) partial pressure gradient. METHODS Four male astronauts on STS-69 (1995) and four on STS-72… read more here.
Keywords: oxygen; oxygen saturation; hemoglobin oxygen; mild hypoxia ... See more keywords
Effects of Normoxia, Hyperoxia, and Mild Hypoxia on Macro-Hemodynamics and the Skeletal Muscle Microcirculation in Anesthetised Rats
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Medicine"
DOI: 10.3389/fmed.2021.672257
Abstract: Objectives: Excessive oxygen (O2) administration may have a negative impact on tissue perfusion by inducing vasoconstriction and oxidative stress. We aimed to evaluate the effects of different inhaled oxygen fractions (FiO2) on macro-hemodynamics and microvascular… read more here.
Keywords: hemodynamics; skeletal muscle; index; mild hypoxia ... See more keywords
Proteobacteria and Firmicutes Secreted Factors Exert Distinct Effects on Pseudomonas aeruginosa Infection under Normoxia or Mild Hypoxia
Sign Up to like & getrecommendations! Published in 2022 at "Metabolites"
DOI: 10.3390/metabo12050449
Abstract: Microbiota may alter a pathogen’s virulence potential at polymicrobial infection sites. Here, we developed a multi-modal Drosophila assay, amenable to the assessment of human bacterial interactions using fly survival or midgut regeneration as a readout,… read more here.
Keywords: pseudomonas aeruginosa; infection; aeruginosa infection; mild hypoxia ... See more keywords