Effect of Rotigotine vs Placebo on Cognitive Functions Among Patients With Mild to Moderate Alzheimer Disease
Sign Up to like & getrecommendations! Published in 2020 at "JAMA Network Open"
DOI: 10.1001/jamanetworkopen.2020.10372
Abstract: This randomized clinical trial evaluates whether treatment with the dopaminergic agonist rotigotine has an effect on cognitive function in patients with mild to moderate Alzheimer disease in Italy. read more here.
Keywords: alzheimer disease; rotigotine; moderate alzheimer; effect ... See more keywords
Effect of Spinal Manipulative and Mobilization Therapies in Young Adults With Mild to Moderate Chronic Low Back Pain
Sign Up to like & getrecommendations! Published in 2020 at "JAMA Network Open"
DOI: 10.1001/jamanetworkopen.2020.12589
Abstract: This randomized clinical trial evaluates the effectiveness of spinal manipulation and spinal mobilization compared with a placebo at reducing pain and disability among young adults with mild to moderate chronic low back pain. read more here.
Keywords: adults mild; young adults; low back; chronic low ... See more keywords
Early Adoption of Anti–SARS-CoV-2 Pharmacotherapies Among US Veterans With Mild to Moderate COVID-19, January and February 2022
Sign Up to like & getrecommendations! Published in 2022 at "JAMA Network Open"
DOI: 10.1001/jamanetworkopen.2022.41434
Abstract: Key Points Question How have antiviral agents and monoclonal antibodies for mild to moderate COVID-19 been used in the Veterans Affairs health care system? Findings In this cohort study of 111 717 outpatient US veterans with… read more here.
Keywords: mild moderate; february 2022; moderate covid; anti sars ... See more keywords
Dual versus mono antiplatelet therapy in mild‐to‐moderate stroke during hospitalization
Sign Up to like & getrecommendations! Published in 2022 at "Annals of Clinical and Translational Neurology"
DOI: 10.1002/acn3.51541
Abstract: Subsequent vascular events are common after acute ischemic stroke during hospitalization . This study aimed to analyze the effectiveness of combination therapy with clopidogrel and aspirin among mild‐to‐moderate ischemic stroke patients treated within 72 h on… read more here.
Keywords: dual versus; mild moderate; stroke hospitalization; therapy ... See more keywords
Quantifying the Human Subchondral Trabecular Bone Microstructure in Osteoarthritis with Clinical CT
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DOI: 10.1002/advs.202201692
Abstract: Osteoarthritis (OA) is characterized by critical alterations of the subchondral bone microstructure, besides the well‐known cartilaginous changes. Clinical computed tomography (CT) detection of quantitative 3D microstructural subchondral bone parameters is applied to monitor changes of… read more here.
Keywords: mild moderate; bone; moderate severe; bone microstructure ... See more keywords
Effect of Varying Degrees of Hepatic Impairment on the Pharmacokinetics of Omecamtiv Mecarbil.
Sign Up to like & getrecommendations! Published in 2021 at "Clinical pharmacology in drug development"
DOI: 10.1002/cpdd.969
Abstract: Omecamtiv mecarbil (OM) is a novel selective cardiac myosin activator under investigation for the treatment of heart failure with reduced ejection fraction. OM is primarily eliminated via metabolism mediated by multiple cytochrome P450 enzymes. This… read more here.
Keywords: omecamtiv mecarbil; hepatic impairment; moderate hepatic; impairment ... See more keywords
Insight into Pain Syndromes in Acute Phase of Mild-to-Moderate COVID-19: Frequency, Clinical Characteristics, and Associated Factors.
Sign Up to like & getrecommendations! Published in 2021 at "European journal of pain"
DOI: 10.1002/ejp.1876
Abstract: BACKGROUND Pain has been frequently described as a clinical feature of COVID-19, and the main pain syndromes that have been associated with the acute phase of this disease so far are headache, myalgia, arthralgia, and… read more here.
Keywords: acute phase; pain; covid; mild moderate ... See more keywords
Effects of adding whole‐body vibration to routine day activity program on physical functioning in elderly with mild or moderate dementia: a randomized controlled trial
Sign Up to like & getrecommendations! Published in 2018 at "International Journal of Geriatric Psychiatry"
DOI: 10.1002/gps.4662
Abstract: To evaluate the effects of whole‐body vibration (WBV) added to a routine activity program on lower limb strength, balance, and mobility among community‐dwelling individuals with mild or moderate dementia, compared with the routine program alone. read more here.
Keywords: body vibration; moderate dementia; program; activity program ... See more keywords
Changes in awareness of condition in people with mild‐to‐moderate dementia: Longitudinal findings from the IDEAL cohort
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Geriatric Psychiatry"
DOI: 10.1002/gps.5702
Abstract: Awareness of difficulties shown by people with dementia is known to vary, but few studies have explored changes in awareness over time. Investigating this could further the understanding of surrounding concepts and reasons for impaired… read more here.
Keywords: mild moderate; awareness condition; condition people; moderate dementia ... See more keywords
Characterization of the Effect of Hepatic Impairment on Upadacitinib Pharmacokinetics
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Clinical Pharmacology"
DOI: 10.1002/jcph.1414
Abstract: Upadacitinib is a selective Janus kinase 1 inhibitor being developed for the treatment of several inflammatory autoimmune diseases, including rheumatoid arthritis. Upadacitinib is a nonsensitive substrate for metabolism by cytochrome P450 3A enzymes. This open‐label,… read more here.
Keywords: hepatic impairment; upadacitinib pharmacokinetics; effect; moderate hepatic ... See more keywords
Efficacy and safety of non-surgical short-wave radiofrequency treatment of mild-to-moderate erythematotelangiectatic rosacea: a prospective, open-label pilot study
Sign Up to like & getrecommendations! Published in 2021 at "Archives of Dermatological Research"
DOI: 10.1007/s00403-021-02225-y
Abstract: Although various treatments have been proposed for the management of rosacea, achieving complete remission of persistent erythema remains challenging. Short-wave radiofrequency (SWRF) treatment has been shown to repair skin barriers and reduce chronic inflammation. However,… read more here.
Keywords: wave radiofrequency; rosacea; short wave; treatment ... See more keywords