Near‐Infrared Light‐Triggered MXene Nanocomposite for Tumor‐Specific Mild Photothermal‐Enhanced Chemodynamic Therapy
Sign Up to like & getrecommendations! Published in 2024 at "Advanced Functional Materials"
DOI: 10.1002/adfm.202405124
Abstract: Mild photothermal therapy (PTT) is an emerging and elegant approach with minimal adverse effects, demonstrating itself as an effective treatment for cancer. However, potential challenges may arise from the overexpression of heat shock protein 90… read more here.
Keywords: therapy; triggered mxene; mild photothermal; tumor ... See more keywords
A Diketopyrrolopyrrole‐Based All‐in‐One Nanoplatform for Self‐Reinforcing Mild Photothermal Therapy Cascade Immunotherapy for Tumors
Sign Up to like & getrecommendations! Published in 2024 at "Advanced Healthcare Materials"
DOI: 10.1002/adhm.202400766
Abstract: Mild photothermal therapy (PTT) has attracted attention for effectively avoiding the severe side effects associated with high‐temperature tumor ablation. However, its progress is hindered by the limited availability of high‐performance photothermal agents (PTAs) and the… read more here.
Keywords: diketopyrrolopyrrole based; mild photothermal; one nanoplatform; nanoplatform ... See more keywords
Engineering Mild‐Photothermal Responsive and NO Donor Prussian Blue Nanozymes Using Mild Synthesis for Inflammation Regulation and Bacterial Eradication in Periodontal Disease
Sign Up to like & getrecommendations! Published in 2024 at "Advanced Materials"
DOI: 10.1002/adma.202409840
Abstract: Periodontitis, an infectious disease of periodontal tissues caused by oral bacterial biofilms, is characterized by reactive oxygen species (ROS) accumulation and immune microenvironment imbalance. Multifunctional nanozymes, leveraging their physiochemical properties and enzymatic activities, offer promising… read more here.
Keywords: temperature; disease; mild photothermal; prussian blue ... See more keywords
Local Exosome Inhibition Potentiates Mild Photothermal Immunotherapy Against Breast Cancer
Sign Up to like & getrecommendations! Published in 2024 at "Advanced Science"
DOI: 10.1002/advs.202406328
Abstract: Limited immune infiltration within the tumor microenvironment (TME) hampers the efficacy of immune checkpoint blockade (ICB) therapy. To enhance immune infiltration, mild photothermal therapy (PTT) is often combined with immunotherapy. However, the impact of mild… read more here.
Keywords: therapy; mild photothermal; cell; infiltration ... See more keywords
Mild Photothermal Bimetallic Mesoporous Nanozyme Triggers Immunogenic Cell Death and Immune Contexture Remodeling for Precision Hepatocellular Carcinoma Treatment.
Sign Up to like & getrecommendations! Published in 2025 at "Advanced science"
DOI: 10.1002/advs.202512578
Abstract: Treating hepatocellular carcinoma (HCC) remains a significant clinical challenge because of its immunosuppressive tumor microenvironment (TME) and poor response to immunotherapy. Immunogenic cell death (ICD) has emerged as a promising strategy for enhancing antitumor immunity… read more here.
Keywords: immunogenic cell; mild photothermal; hepatocellular carcinoma; cell ... See more keywords
Near Infrared-Triggered Theranostic Nanoplatform with Controlled Release of HSP90 Inhibitor for Synergistic Mild Photothermal and Enhanced Nanocatalytic Therapy with Hypoxia Relief.
Sign Up to like & getrecommendations! Published in 2022 at "Small"
DOI: 10.1002/smll.202200786
Abstract: Mild photothermal therapy (PTT, 50 °C). However, its therapeutic efficacy is limited owing to the hypoxic tumor environment and tumor thermoresistance owing to the overproduction of heat shock proteins (HSPs). Herein, a near-infrared (NIR)-triggered theranostic nanoplatform… read more here.
Keywords: hsp90; therapy; triggered theranostic; mild photothermal ... See more keywords
Transmembrane MUC18 Targeted Polydopamine Nanoparticles and a Mild Photothermal Effect Synergistically Disrupt Actin Cytoskeleton and Migration of Cancer Cells.
Sign Up to like & getrecommendations! Published in 2021 at "Nano letters"
DOI: 10.1021/acs.nanolett.1c03377
Abstract: Transmembrane MUC18 is highly expressed on most metastatic cancers. Herein, we demonstrate that targeting MUC18 with polydopamine nanoparticles (PDA NPs) and a mild photothermal effect can completely cease the migration of melanoma and breast cancer… read more here.
Keywords: actin cytoskeleton; transmembrane muc18; effect; migration ... See more keywords
Cancer Cell-Mimicking Prussian Blue Nanoplatform for Synergistic Mild Photothermal/Chemotherapy via Heat Shock Protein Inhibition.
Sign Up to like & getrecommendations! Published in 2024 at "ACS applied materials & interfaces"
DOI: 10.1021/acsami.4c00873
Abstract: Combined mild-temperature photothermal/chemotherapy has emerged as a highly promising modality for tumor therapy. However, its therapeutic efficacy is drastically compromised by the heat-induced overexpression of heat shock proteins (HSPs) by the cells, which resist heat… read more here.
Keywords: photothermal chemotherapy; heat; mild photothermal; chemotherapy ... See more keywords
Core-Satellite Nanocomposites Synchronize Mild Photothermal Disruption and ROS Scavenging for Periodontal Microenvironment Rebalancing.
Sign Up to like & getrecommendations! Published in 2025 at "ACS applied materials & interfaces"
DOI: 10.1021/acsami.5c09922
Abstract: Given the inherent microbial environment of the oral cavity, therapeutic strategies necessitate transcending conventional antimicrobial approaches to prioritize the restoration of immune homeostasis in periodontal microenvironments. Specifically, excess reactive oxygen species (ROS) generated from the… read more here.
Keywords: mild photothermal; core satellite; ros scavenging; microenvironment ... See more keywords
Reversing the Epithelial-Mesenchymal Transition in Metastatic Cancer Cells Using CD146-Targeted Black Phosphorus Nanosheets and a Mild Photothermal Treatment.
Sign Up to like & getrecommendations! Published in 2022 at "ACS nano"
DOI: 10.1021/acsnano.1c11070
Abstract: Cancer metastasis leads to most deaths in cancer patients, and the epithelial-mesenchymal transition (EMT) is the key mechanism that endows the cancer cells with strong migratory and invasive abilities. Here, we present a nanomaterial-based approach… read more here.
Keywords: cancer; cd146; mild photothermal; photothermal treatment ... See more keywords
"Electron Transport Chain Interference" Strategy of Amplified Mild-Photothermal Therapy and Defect-Engineered Multi-Enzymatic Activities for Synergistic Tumor-Personalized Suppression.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of the American Chemical Society"
DOI: 10.1021/jacs.2c09608
Abstract: Arming activatable mild-photothermal therapy (PTT) with the property of relieving tumor thermotolerance holds great promise for overcoming traditional mild PTT limitations such as thermoresistance, insufficient therapeutic effect, and off-target heating. Herein, a mitochondria-targeting, defect-engineered AFCT… read more here.
Keywords: photothermal therapy; multi enzymatic; therapy; defect engineered ... See more keywords