Milk‐derived extracellular vesicles functionalized with anti‐tumour necrosis factor‐α nanobody and anti‐microbial peptide alleviate ulcerative colitis in mice
Sign Up to like & getrecommendations! Published in 2024 at "Journal of Extracellular Vesicles"
DOI: 10.1002/jev2.12462
Abstract: Abstract Ulcerative colitis (UC) manifests clinically with chronic intestinal inflammation and microflora dysbiosis. Although biologics can effectively control inflammation, efficient delivery to the colon and colon epithelial cells remains challenging. Milk‐derived extracellular vesicles (EV) show… read more here.
Keywords: extracellular vesicles; tumour necrosis; milk derived; derived extracellular ... See more keywords
Milk-derived anti-infectives and their potential to combat bacterial and viral infection
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Functional Foods"
DOI: 10.1016/j.jff.2021.104442
Abstract: Abstract Breastfeeding positively influences infant growth while providing protection against many diseases. Breast milk provides the ideal balance of nutrients for the infant and contains countless bioactive ingredients such as immunoglobulins (antibodies), fatty acids, oligosaccharides… read more here.
Keywords: milk; bovine milk; infection; anti infectives ... See more keywords
Milk-Derived Extracellular Vesicles: Biomedical Applications, Current Challenges, and Future Perspectives.
Sign Up to like & getrecommendations! Published in 2024 at "Journal of agricultural and food chemistry"
DOI: 10.1021/acs.jafc.3c07899
Abstract: Extracellular vesicles (EVs) are nano to-micrometer-sized sacs that are released by almost all animal and plant cells and act as intercellular communicators by transferring their cargos between the source and target cells. As a safe… read more here.
Keywords: extracellular vesicles; mievs; biomedical applications; milk derived ... See more keywords
Development and In Vitro Characterization of Milk-Derived Extracellular Vesicle-Mithramycin Formulations for Potential Glioma Therapy.
Sign Up to like & getrecommendations! Published in 2025 at "Molecular pharmaceutics"
DOI: 10.1021/acs.molpharmaceut.4c01189
Abstract: Glioblastoma (GBM) is a highly aggressive brain tumor with resistance to conventional therapies. Mithramycin (Mit-A), a potent antitumor agent, has shown promise in several tumor types including, GBM. However, its clinical application is limited by… read more here.
Keywords: mev mit; mit; milk derived; derived extracellular ... See more keywords
Natural Soybean Milk-Derived Bioactive Coatings for Enhanced Wound Healing.
Sign Up to like & getrecommendations! Published in 2022 at "ACS applied materials & interfaces"
DOI: 10.1021/acsami.2c09689
Abstract: Foodborne biomaterials, derived from diets, comprise selfassembled collections of many micro- or nanoscale units with abundant nutrients and active substances. In this study, soybean milk (SBM) was selected as a tissue engineering product for simple… read more here.
Keywords: wound healing; derived bioactive; soybean milk; milk derived ... See more keywords
Nanotherapy for bone repair: milk-derived small extracellular vesicles delivery of icariin
Sign Up to like & getrecommendations! Published in 2023 at "Drug Delivery"
DOI: 10.1080/10717544.2023.2169414
Abstract: Abstract Icariin (ICA) played an important role in the treatment of inflammatory bone defects. However, pharmacokinetic studies have shown that its poor bioavailability limited its application. In this context, we isolated bovine milk-derived sEV and… read more here.
Keywords: ica; bone; sev ica; milk derived ... See more keywords
Association of breast milk-derived arachidonic acid-induced infant gut dysbiosis with the onset of atopic dermatitis
Sign Up to like & getrecommendations! Published in 2024 at "Gut"
DOI: 10.1136/gutjnl-2024-332407
Abstract: Objective The specific breast milk-derived metabolites that mediate host–microbiota interactions and contribute to the onset of atopic dermatitis (AD) remain unknown and require further investigation. Design We enrolled 250 mother–infant pairs and collected 978 longitudinal… read more here.
Keywords: gut dysbiosis; breast milk; milk derived; milk ... See more keywords
Cow milk derived-fat inhibits the proliferation of liver cancer-cells
Sign Up to like & getrecommendations! Published in 2024 at "Applied Biological Chemistry"
DOI: 10.1186/s13765-024-00860-3
Abstract: Cow milk is a widely consumed liquid diet, and its fatty acid composition impacts its nutritional and biochemical properties. However, research on the anticancer efficacy of cow milk-derived fat in liver cancer cells is limited.… read more here.
Keywords: cow milk; milk derived; liver cancer; derived fat ... See more keywords
Breast milk-derived extracellular vesicle miRNAs are associated with maternal asthma and atopy.
Sign Up to like & getrecommendations! Published in 2022 at "Epigenomics"
DOI: 10.2217/epi-2022-0090
Abstract: Background: Breast milk-derived extracellular vesicle (EV) miRNAs may program child health outcomes associated with maternal asthma and atopy. The authors investigated associations between maternal asthma/atopy and EV miRNAs in the Programming of Intergenerational Stress Mechanisms… read more here.
Keywords: maternal asthma; asthma atopy; breast milk; milk derived ... See more keywords
Short communication: Dietary bovine milk-derived exosomes improve bone health in an osteoporosis-induced mouse model.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of dairy science"
DOI: 10.3168/jds.2019-17501
Abstract: Osteoporosis is a systemic skeletal disease characterized by low bone mass and micro-architectural deterioration of bone tissue, with a consequent increase in bone fragility and fracture susceptibility. In an aged society with increased life expectancy,… read more here.
Keywords: bovine; bone; milk derived; derived exosomes ... See more keywords
Yak milk-derived exosomal miRNAs regulate intestinal epithelial cells on proliferation in hypoxic environment.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of dairy science"
DOI: 10.3168/jds.2020-19063
Abstract: Intestinal epithelial cells (IEC) act as an important intestinal barrier whose function can be impaired upon induction by hypoxia. Although intestinal barrier injuries are preventable by milk-derived exosomal microRNAs (miRNAs), the underlying mechanism remains poorly… read more here.
Keywords: milk; yak milk; derived exosomal; hypoxia ... See more keywords