Genome-wide association analyses of posttraumatic stress disorder and its symptom subdomains in the Million Veteran Program
Sign Up to like & getrecommendations! Published in 2021 at "Nature genetics"
DOI: 10.1038/s41588-020-00767-x
Abstract: We conducted genome-wide association analyses in over 250,000 participants of European and African ancestry from the Million Veteran Program using electronic health record-validated posttraumatic stress disorder (PTSD) diagnosis and quantitative symptom phenotypes. Applying genome-wide multiple… read more here.
Keywords: genome wide; million veteran; symptom; association analyses ... See more keywords
Longitudinal Drinking Patterns and Their Clinical Correlates in Million Veteran Program Participants
Sign Up to like & getrecommendations! Published in 2019 at "Alcoholism: Clinical and Experimental Research"
DOI: 10.1111/acer.13951
Abstract: BACKGROUND A variety of measures have been developed to screen for hazardous or harmful drinking. The Alcohol Use Disorders Identification Test-Consumption (AUDIT-C) is one of the screening measures recommended by the U.S. Preventive Services Task… read more here.
Keywords: drinking; million veteran; group; audit ... See more keywords
Pharmacogenetic variants and risk of remdesivir‐associated liver enzyme elevations in Million Veteran Program participants hospitalized with COVID‐19
Sign Up to like & getrecommendations! Published in 2022 at "Clinical and Translational Science"
DOI: 10.1111/cts.13313
Abstract: Remdesivir is the first US Food and Drug Administration (FDA)‐approved drug for the treatment of coronavirus disease 2019 (COVID‐19). We conducted a retrospective pharmacogenetic study to examine remdesivir‐associated liver enzyme elevation among Million Veteran Program… read more here.
Keywords: remdesivir associated; liver enzyme; associated liver; program participants ... See more keywords
Abstract 012: Performance of Polygenic Risk Scores for Coronary Artery Disease in the Million Veteran Program
Sign Up to like & getrecommendations! Published in 2019 at "Circulation"
DOI: 10.1161/circ.139.suppl_1.012
Abstract: Introduction: Recent studies suggest a substantial improvement in risk prediction of coronary artery disease (CAD) with polygenic risk scores (PRS). The degree to which this improvement is generalizable to other European (EUR) and non-EUR populations… read more here.
Keywords: artery disease; coronary artery; risk; polygenic risk ... See more keywords
Genome-wide association study identifies four pan-ancestry loci for suicidal ideation in the Million Veteran Program
Sign Up to like & getrecommendations! Published in 2023 at "PLOS Genetics"
DOI: 10.1371/journal.pgen.1010623
Abstract: Suicidal ideation (SI) often precedes and predicts suicide attempt and death, is the most common suicidal phenotype and is over-represented in veterans. The genetic architecture of SI in the absence of suicide attempt (SA) is… read more here.
Keywords: ancestry; suicidal ideation; veteran program; analysis ... See more keywords
Million Veteran Program’s response to COVID-19: Survey development and preliminary findings
Sign Up to like & getrecommendations! Published in 2022 at "PLoS ONE"
DOI: 10.1371/journal.pone.0266381
Abstract: Background In response to the novel Coronavirus Disease 2019 (COVID-19) pandemic, the Department of Veterans Affairs (VA) Million Veteran Program (MVP) organized efforts to better understand the impact of COVID-19 on Veterans by developing and… read more here.
Keywords: covid survey; survey; covid; veteran program ... See more keywords
Genetic Loci Associated With COVID-19 Positivity and Hospitalization in White, Black, and Hispanic Veterans of the VA Million Veteran Program
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Genetics"
DOI: 10.3389/fgene.2021.777076
Abstract: SARS-CoV-2 has caused symptomatic COVID-19 and widespread death across the globe. We sought to determine genetic variants contributing to COVID-19 susceptibility and hospitalization in a large biobank linked to a national United States health system.… read more here.
Keywords: covid positivity; covid; veteran program; hospitalization ... See more keywords