Transthyretin Mimetics as Anti‐β‐Amyloid Agents: A Comparison of Peptide and Protein Approaches
Sign Up to like & getrecommendations! Published in 2018 at "ChemMedChem"
DOI: 10.1002/cmdc.201800031
Abstract: β‐Amyloid (Aβ) aggregation is causally linked to neuronal pathology in Alzheimer's disease; therefore, several small molecules, antibodies, and peptides have been tested as anti‐Aβ agents. We developed two compounds based on the Aβ‐binding domain of… read more here.
Keywords: protein; mimetics anti; transthyretin mimetics; cg8 ... See more keywords
Recent advances in the field of caloric restriction mimetics and anti-aging molecules
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DOI: 10.1016/j.arr.2020.101240
Abstract: Caloric restriction (CR) mimetics are molecules that produce beneficial effects on health and longevity in model organisms and humans, without the challenges of maintaining a CR diet. Conventional CR mimetics such as metformin, rapamycin and… read more here.
Keywords: mimetics anti; aging molecules; restriction mimetics; caloric restriction ... See more keywords