Depleting T regulatory cells by targeting intracellular Foxp3 with a TCR mimic antibody
Sign Up to like & getrecommendations! Published in 2019 at "Oncoimmunology"
DOI: 10.1080/2162402x.2019.1570778
Abstract: ABSTRACT Depletion of T regulatory cells (Tregs) in the tumor microenvironment is a promising cancer immunotherapy strategy. Current approaches for depleting Tregs are limited by lack of specificity and concurrent depletion of anti-tumor effector T… read more here.
Keywords: foxp3; mimic antibody; antibody; intracellular foxp3 ... See more keywords
A peptide mimic of an antibody
Sign Up to like & getrecommendations! Published in 2017 at "Science"
DOI: 10.1126/science.aap9608
Abstract: Antibody miniaturization leads to a cyclic peptide that neutralizes influenza viruses Influenza virus is one of the largest public health concerns. There is no universal vaccine, and only a few small-molecule drugs are available for… read more here.
Keywords: peptide mimic; mimic antibody; antibody; molecule ... See more keywords