An ADAR2-mimic base editor for efficient C-to-U RNA editing in vivo.
Sign Up to like & getrecommendations! Published in 2025 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2505269122
Abstract: RNA base editing has the capability to rewrite genetic codes while offering improved safety due to its reversibility and temporal-spatial tunability. The development of cytosine-to-uridine editors faces issues of DNA mutagenic activity of APOBECs and… read more here.
Keywords: mimic base; rna editing; rna; base editor ... See more keywords