A TCR Mimic CAR T Cell Specific for NDC80 Is Broadly Reactive With Solid Tumors and Hematological Malignancies.
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DOI: 10.1182/blood.2021012882
Abstract: Target identification for CAR T cell therapies remains challenging due to the limited repertoire of tumor-specific surface proteins. Intracellular proteins presented in the context of cell surface HLA provide a wide pool of potential antigens… read more here.
Keywords: broadly reactive; mimic car; tcr mimic; cell ... See more keywords