Mimicking Cellular Signaling Pathways within Synthetic Multicompartment Vesicles with Triggered Enzyme Activity and Induced Ion Channel Recruitment
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DOI: 10.1002/adfm.201904267
Abstract: Subcellular compartmentalization of cells, a defining characteristic of eukaryotes, is fundamental for the fine tuning of internal processes and the responding to external stimuli. Reproducing and controlling such compartmentalized hierarchical organization, responsiveness, and communication is… read more here.
Keywords: signaling pathways; cellular signaling; activity; multicompartment ... See more keywords
Macrophage‐Mimicking Cellular Nanoparticles Scavenge Proinflammatory Cytokines in Specimens of Patients with Inflammatory Disorders
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DOI: 10.1002/advs.202401423
Abstract: Effectively neutralizing inflammatory cytokines is crucial for managing a variety of inflammatory disorders. Current techniques that target only a subset of cytokines often fall short due to the intricate nature of redundant and compensatory cytokine… read more here.
Keywords: mimicking cellular; macrophage mimicking; inflammatory cytokines; inflammatory ... See more keywords
Mimicking the cellular environment does not cause monocyte‐derived macrophages to become phenotypically similar to Kupffer cells
Sign Up to like & getrecommendations! Published in 2024 at "Immunology and Cell Biology"
DOI: 10.1111/imcb.12746
Abstract: Resident macrophages of various mammalian organs are characterized by several distinctive features in their gene expression profile and phenotype, including involvement in the regulation of organ functions, as well as reduced sensitivity to proinflammatory activation… read more here.
Keywords: kupffer cells; derived macrophages; monocyte derived; mimicking cellular ... See more keywords