Cystatin C in addition to creatinine for better assessment of glomerular renal function decline in people with HIV receiving antiretroviral therapy
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DOI: 10.1097/qad.0000000000003434
Abstract: Objective: To compare the estimated glomerular filtration rate (eGFR) using the creatinine equation (eGFRcreat) or the cystatin C equation (eGFRcys) in people with HIV (PWH) under antiretroviral drugs. We specifically included patients with an eGFRcreat… read more here.
Keywords: egfrcreat; antiretroviral drugs; people hiv; min per ... See more keywords
Characterization of Enzymes Involved in Nintedanib Metabolism in Humans
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DOI: 10.1124/dmd.122.001113
Abstract: Nintedanib, which is used to treat idiopathic pulmonary fibrosis and non–small cell lung cancer, is metabolized to a pharmacologically inactive carboxylate derivative, BIBF1202, via hydrolysis and subsequently by glucuronidation to BIBF1202 acyl-glucuronide (BIBF1202-G). Since BIBF1202-G… read more here.
Keywords: glucuronidation; min per; nintedanib metabolism; bibf1202 ... See more keywords
Ongoing Exercise Intolerance Following COVID-19: A Magnetic Resonance-Augmented Cardiopulmonary Exercise Test Study.
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DOI: 10.1161/jaha.121.024207
Abstract: Background Ongoing exercise intolerance of unclear cause following COVID-19 infection is well recognized but poorly understood. We investigated exercise capacity in patients previously hospitalized with COVID-19 with and without self-reported exercise intolerance using magnetic resonance-augmented… read more here.
Keywords: resonance augmented; cardiopulmonary exercise; magnetic resonance; min per ... See more keywords
CKD: A Call for an Age-Adapted Definition.
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DOI: 10.1681/asn.2019030238
Abstract: Current criteria for the diagnosis of CKD in adults include persistent signs of kidney damage, such as increased urine albumin-to-creatinine ratio or a GFR below the threshold of 60 ml/min per 1.73 m2 This threshold… read more here.
Keywords: ckd; min per; age; kidney damage ... See more keywords
Think Twice before Postponing Chronic Dialysis in Children.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of the American Society of Nephrology : JASN"
DOI: 10.1681/asn.2019090895
Abstract: The article by Winnicki et al.1 and the related editorial by Larkins and Craig2 raises important questions about indiscriminately postponing dialysis in children in every clinical setting. Multiple studies have shown that the global variation… read more here.
Keywords: dialysis children; peritoneal dialysis; dialysis; nephrology ... See more keywords
Trajectories of Kidney Function in Patients with ATTRv Treated with Gene Silencers
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DOI: 10.3390/genes13122236
Abstract: Hereditary transthyretin amyloidosis (ATTRv; v for “variant”) is the most common form of hereditary amyloidosis, with an autosomal dominant inheritance and a variable penetrance. This disease has a significant variability in clinical presentation and multiorgan… read more here.
Keywords: function; trajectories kidney; min per; kidney function ... See more keywords
Sedentary Behavior Patterns of the Hungarian Adult Population
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DOI: 10.3390/ijerph20032702
Abstract: Background and aim: Nowadays, a high level of sedentary behavior (SB) is an important health issue. Many studies have focused on evaluating the physical activity (PA) level, while evaluation of SB has received less attention.… read more here.
Keywords: per day; sedentary behavior; min per; sitting time ... See more keywords