Characterization of Clofazimine as a Potential Substrate of Drug Transporter
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DOI: 10.1128/aac.02158-21
Abstract: In this study, we explored clofazimine (CFZ) as a potential substrate of uptake and efflux transporters that might be involved in CFZ disposition, using transporter gene overexpressing cell lines in vitro. The intracellular concentrations of… read more here.
Keywords: cell lines; pmol min; min protein; potential substrate ... See more keywords
Large-scale modulation of reconstituted Min protein patterns and gradients by defined mutations in MinE’s membrane targeting sequence
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DOI: 10.1371/journal.pone.0179582
Abstract: The E. coli MinDE oscillator is a paradigm for protein self-organization and gradient formation. Previously, we reconstituted Min protein wave patterns on flat membranes as well as gradient-forming pole-to-pole oscillations in cell-shaped PDMS microcompartments. These… read more here.
Keywords: protein; reconstituted min; membrane targeting; min protein ... See more keywords