A Window into Your Gut: Biologically Inspired Engineering of Mini-gut Tubes In Vitro.
Sign Up to like & getrecommendations! Published in 2020 at "Developmental cell"
DOI: 10.1016/j.devcel.2020.11.015
Abstract: Recently in Nature, using biologically inspired design principles to recapitulate native crypt-villi topography and luminal flow, Nikolaev et al. engineered an intestinal organotypic culture system that is capable of long-term epithelial homeostasis. Mini-gut tubes were used… read more here.
Keywords: gut; window gut; biologically inspired; mini gut ... See more keywords
Mini-gut: a promising model for drug development.
Sign Up to like & getrecommendations! Published in 2019 at "Drug discovery today"
DOI: 10.1016/j.drudis.2019.06.006
Abstract: Until recently, major advances in drug development have been hampered by a lack of proper cell and tissue models; but the introduction of organoid technology has revolutionized this field. At the level of the gastrointestinal… read more here.
Keywords: drug; drug development; development; mini gut ... See more keywords