Development and In Vitro Evaluation of a Novel Pulsatile Drug Delivery System Containing Dexketoprofen Trometamol
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Pharmaceutical Innovation"
DOI: 10.1007/s12247-020-09452-2
Abstract: Purpose A pulsatile drug delivery system containing dexketoprofen trometamol was designed by combining immediate release and colon-targeted mini tablets into a capsule. Methods Both immediate release and colon-targeted mini tablets were prepared by wet granulation.… read more here.
Keywords: mini tablets; dexketoprofen trometamol; colon targeted; colon ... See more keywords
Decoding the Small Size Challenges of Mini-tablets for Enhanced Dose Flexibility and Micro-dosing.
Sign Up to like & getrecommendations! Published in 2019 at "International journal of pharmaceutics"
DOI: 10.1016/j.ijpharm.2019.118905
Abstract: Mini-tablets are an age appropriate dosage form for oral administration to pediatric and geriatric patients, either as individual mini-tablets or as composite dosage units. Smaller mini-tablets than the commonly used 2 mm or larger size… read more here.
Keywords: tablets enhanced; mini tablets; flexibility; size ... See more keywords
Development of piroxicam mini-tablets enabled by spherical cocrystallization.
Sign Up to like & getrecommendations! Published in 2020 at "International journal of pharmaceutics"
DOI: 10.1016/j.ijpharm.2020.119953
Abstract: We examined the potential of the spherical cocrystallization (SCC) technology in simultaneously enhancing tablet manufacturability and dissolution of poorly soluble drugs by developing a mini-tablet formulation of piroxicam. The manufacturing of mini-tablets using a direct… read more here.
Keywords: mini tablets; spherical cocrystallization; prx; development ... See more keywords
Drotaverine hydrochloride gastroretentive floating mini-tablets: Formulation, in-vitro and in-vivo evaluation
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Drug Delivery Science and Technology"
DOI: 10.1016/j.jddst.2020.101733
Abstract: Abstract Drotaverine hydrochloride (DRH) is an antispasmodic drug which has a short residence in the intestine during diarrhea that prompts poor bioavailability and frequent dosing. The aim of the present study was to increase the… read more here.
Keywords: sodium; drotaverine hydrochloride; mini tablets; floating mini ... See more keywords
Evaluation of dissolution techniques for orally disintegrating mini-tablets
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DOI: 10.1016/j.jddst.2020.102191
Abstract: Abstract Mini-tablets are suitable for paediatric as well as geriatric use since they may provide flexible and accurate dosing and administration. Due to the minute tablet size, there is a need for new standardized quality… read more here.
Keywords: orally disintegrating; dissolution techniques; mini tablets; techniques orally ... See more keywords
Mini-tablets as technological strategy for modified release of morphine sulfate
Sign Up to like & getrecommendations! Published in 2022 at "Pharmaceutical Development and Technology"
DOI: 10.1080/10837450.2022.2118769
Abstract: Abstract This study aimed to use an intelligent formulation design for the development of mini-tablets for the modified release of morphine sulfate. A formulation (F1) was proposed using the Hiperstart® software. Based on the suggested… read more here.
Keywords: mini tablets; morphine sulfate; release; formulation ... See more keywords
Acceptability of multiple coated mini-tablets in comparison to syrup in infants and toddlers: a randomised controlled study
Sign Up to like & getrecommendations! Published in 2023 at "Archives of Disease in Childhood"
DOI: 10.1136/archdischild-2022-325264
Abstract: Objectives Drug treatment of children is often limited to liquid formulations or manipulation of adult solid oral dosage forms because of the lack of age-appropriate formulations, concerns around particle aspiration and paediatric acceptability. Recent research… read more here.
Keywords: acceptability; multiple coated; mini tablets; coated mini ... See more keywords
Glibenclamide Mini-tablets with an Enhanced Pharmacokinetic and Pharmacodynamic Performance
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DOI: 10.1208/s12249-018-1108-y
Abstract: In an attempt to decrease the dose, anticipated side effects, and the cost of production of glibenclamide, GLC, a potent oral hypoglycemic drug, the enhancement of the dissolution and hence the oral bioavailability were investigated.… read more here.
Keywords: glibenclamide; adsorption; oral bioavailability; mini tablets ... See more keywords
Mini-Tablets versus Nanoparticles for Controlling the Release of Amoxicillin: In vitro/In vivo Study
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DOI: 10.2147/dddt.s285522
Abstract: Introduction Controlling the drug release from the dosage form at a definite rate is the main challenge for a successful oral controlled-release drug delivery system. In this study, mini-tablets (MTs) and lipid/polymer nanoparticles (LPNs) of… read more here.
Keywords: lipid polymer; drug; study mini; mini tablets ... See more keywords
New Orodispersible Mini Tablets of Enalapril Maleate by Direct Compression for Pediatric Patients.
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DOI: 10.2174/1567201817666200508093442
Abstract: BACKGROUND In many countries, the hypertension in the pediatric population is considered an important risk of mortality and morbidity. In this sense, it is important to design and develop new pharmaceutical forms for pediatric patients… read more here.
Keywords: mini tablets; enalapril maleate; tablets enalapril; orodispersible mini ... See more keywords
OPTIMIZING FORMULATION OF MINI TABLETS FLOATING RANITIDINE HCL USING FULLY PREGELATINIZED STARCH (MANIHOT ESCULENTA CRANTZ) WITH SIMPLEX LATTICE DESIGN
Sign Up to like & getrecommendations! Published in 2019 at "International Journal of Applied Pharmaceutics"
DOI: 10.22159/ijap.2019v11i4.32657
Abstract: Objective: The main objective of this study was to optimize the noneffervescent floating mini tablets (NEFT) formula of ranitidine hydrochloride (ranitidine HCl) using the simplex lattice design (SLD) with parameters, granule flow rate, hardness, friability,… read more here.
Keywords: ranitidine; mini tablets; hcl; ranitidine hcl ... See more keywords