High minichromosome maintenance protein 7 proliferation indices: a powerful predictor of progression in pancreatic neuroendocrine neoplasms without distant metastasis at the time of surgery.
Sign Up to like & getrecommendations! Published in 2019 at "Human pathology"
DOI: 10.1016/j.humpath.2018.10.027
Abstract: Pancreatic neuroendocrine neoplasms (PanNENs) have an unpredictable clinical course that varies from indolent to highly malignant. No immunohistochemical markers are available for reliable prediction of the biological behavior of early stage PanNENs. Minichromosome maintenance protein… read more here.
Keywords: index; pancreatic neuroendocrine; neuroendocrine neoplasms; progression ... See more keywords
Diagnosis of pancreaticobiliary malignancy by detection of minichromosome maintenance protein 5 in biliary brush cytology
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DOI: 10.1038/bjc.2016.447
Abstract: Background:Biliary brush cytology is the standard method of evaluating biliary strictures, but is insensitive at detecting malignancy. In pancreaticobiliary cancer minichromosome maintenance replication proteins (MCM 2–7) are dysregulated in the biliary epithelium and MCM5 levels… read more here.
Keywords: minichromosome maintenance; malignancy; biliary brush; cytology ... See more keywords
Unwinding 20 Years of the Archaeal Minichromosome Maintenance Helicase
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DOI: 10.1128/jb.00729-19
Abstract: Replicative DNA helicases are essential cellular enzymes that unwind duplex DNA in front of the replication fork during chromosomal DNA replication. Replicative helicases were discovered, beginning in the 1970s, in bacteria, bacteriophages, viruses, and eukarya,… read more here.
Keywords: unwinding years; dna; replication; helicase ... See more keywords
The High Expression of Minichromosome Maintenance Complex Component 5 Is an Adverse Prognostic Factor in Lung Adenocarcinoma
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DOI: 10.1155/2022/4338793
Abstract: Background Minichromosome maintenance (MCM) genes are crucial for genomic DNA replication and are important biomarkers in tumor biology. In this study, we aimed to identify the diagnostic, therapeutic, and prognostic value of the MCM2–10 genes… read more here.
Keywords: cancer; expression; minichromosome maintenance; lung cancer ... See more keywords
Bioinformatics analysis of the transcriptional expression of minichromosome maintenance proteins as potential indicators of survival in patients with cervical cancer
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DOI: 10.1186/s12885-021-08674-y
Abstract: Background As major regulators of DNA replication in eukaryotes, minichromosome maintenance (MCM) proteins play an important role in the initiation and extension of DNA replication. MCMs and their related genes may be new markers of… read more here.
Keywords: cervical cancer; mcms; expression; related genes ... See more keywords
MCM4 is a novel prognostic biomarker and promotes cancer cell growth in glioma
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DOI: 10.3389/fonc.2022.1004324
Abstract: Background Gliomas account for 75% of all primary malignant brain tumors in adults and result in high mortality. Accumulated evidence has declared the minichromosome maintenance protein complex (MCM) gene family plays a critical role in… read more here.
Keywords: cell; mcms; minichromosome maintenance; glioma ... See more keywords
Minichromosome maintenance protein 10 as a marker for proliferation and prognosis in lung cancer.
Sign Up to like & getrecommendations! Published in 2019 at "International journal of oncology"
DOI: 10.3892/ijo.2019.4899
Abstract: DNA replication is a vital process in cell division where anomalies can lead to tumorigenesis. Minichromosome maintenance complex component 10 (MCM10) plays a crucial role in this process. However, the role of MCM10 in lung cancer… read more here.
Keywords: mcm10; expression; lung cancer; cancer ... See more keywords