Splicing Analysis of 16 PALB2 ClinVar Variants by Minigene Assays: Identification of Six Likely Pathogenic Variants
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DOI: 10.3390/cancers14184541
Abstract: Simple Summary PALB2 pathogenic variants confer high risk of breast cancer. Here, we have analyzed the impact of PALB2 variants on splicing, a gene expression step that removes introns to form the mature messenger RNA.… read more here.
Keywords: pathogenic variants; palb2 variants; minigene assays; palb2 ... See more keywords