A minigene DNA vaccine encoding peptide epitopes derived from Galectin-1 has protective antitumoral effects in a model of neuroblastoma.
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DOI: 10.1016/j.canlet.2021.03.020
Abstract: We recently identified Galectin-1 (Gal-1), a β-galactoside-binding lectin, as a novel immune regulator in neuroblastoma (NB). Here, we characterized the tolerogenic function of Gal-1 within the CD8+ T cell compartment and further evaluated its relevance… read more here.
Keywords: minigene dna; dna; encoding peptide; vaccine encoding ... See more keywords