Significance of recurrence of minimal residual disease detected by multi‐parameter flow cytometry in patients with acute lymphoblastic leukemia in morphological remission
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DOI: 10.1002/ajh.24629
Abstract: We sought to determine the significance of minimal residual disease (MRD) relapse in patients with ALL after achieving MRD negative status following induction and consolidation therapy. Between January 2003 and September 2014, 647 newly diagnosed… read more here.
Keywords: multi parameter; minimal residual; recurrence; remission ... See more keywords
Minimal residual disease status determined by multiparametric flow cytometry pretransplantation predicts the outcome of patients with ALL receiving unmanipulated haploidentical allografts
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DOI: 10.1002/ajh.25417
Abstract: This study evaluated the effects of pretransplantation minimal residual disease (pre‐MRD) on outcomes of patients with acute lymphoblastic leukemia (ALL) who underwent unmanipulated haploidentical stem cell transplantation (haplo‐SCT). A retrospective study including 543 patients with… read more here.
Keywords: cir; minimal residual; mrd; disease ... See more keywords
Imaging and bone marrow assessments improve minimal residual disease prediction in multiple myeloma
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DOI: 10.1002/ajh.25507
Abstract: The value of minimal residual disease (MRD) status by bone marrow and imaging analysis as independent prognostic factors has been well established in multiple myeloma (MM). Nevertheless data about their potential complementarity for a more… read more here.
Keywords: pet; mrd pet; minimal residual; residual disease ... See more keywords
Impact of minimal residual negativity using next generation flow cytometry on outcomes in light chain amyloidosis
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DOI: 10.1002/ajh.25746
Abstract: We evaluated bone marrow minimal residual disease (MRD) negativity in 44 patients with light chain (AL) amyloidosis using next generation flow cytometry (sensitivity ≥1 × 10−5; median events analyzed: 8.7 million, range: 4.8 to 9.7 million). All… read more here.
Keywords: minimal residual; mrd; response; mrd negative ... See more keywords
SARS‐CoV‐2 vaccination induces breakthrough hemolysis in paroxysmal nocturnal hemoglobinuria on complement inhibitor
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DOI: 10.1002/ajh.26262
Abstract: 1. Avet-Loiseau H, San-Miguel J, Casneuf T, et al. Evaluation of sustained minimal residual disease negativity with daratumumabcombination regimens in relapsed and/or refractory multiple myeloma: analysis of POLLUX and CASTOR. J Clin Oncol. 2021;39(10): 1139-1149.… read more here.
Keywords: minimal residual; myeloma; multiple myeloma; residual disease ... See more keywords
Identification of critical hemodilution by artificial intelligence in bone marrow assessed for minimal residual disease analysis in acute myeloid leukemia: The Cinderella method
Sign Up to like & getrecommendations! Published in 2022 at "Cytometry Part A"
DOI: 10.1002/cyto.a.24686
Abstract: Minimal residual disease (MRD) detection is a strong predictor for survival and relapse in acute myeloid leukemia (AML). MRD can be either determined by molecular assessment strategies or via multiparameter flow cytometry. The degree of… read more here.
Keywords: residual disease; minimal residual; hemodilution; mrd ... See more keywords
Potential loss of prognostic significance of minimal residual disease assessment after R‐CHOP‐based induction in elderly patients with mantle cell lymphoma in the era of rituximab maintenance
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DOI: 10.1002/hon.2550
Abstract: Rituximab maintenance (RM) prolongs survival of elderly patients with mantle cell lymphoma (MCL). Persistent minimal residual disease (MRD) after induction repeatedly correlated with shorter progression‐free survival (PFS). However, none of the published studies analyzed patients… read more here.
Keywords: minimal residual; residual disease; elderly patients; induction ... See more keywords
PCR Technology to Identify Minimal Residual Disease.
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DOI: 10.1007/978-1-0716-0810-4_6
Abstract: Although new techniques (i.e., droplet digital-PCR, next-generation sequencing, advanced flow cytometry) are being developed, DNA-based allele-specific real-time quantitative (RQ)-PCR is still the gold standard for sensitive and accurate immunoglobulin/T cell receptor (IG/TR)-based minimal residual disease… read more here.
Keywords: minimal residual; pcr; residual disease; technology identify ... See more keywords
Imaging of treatment response and minimal residual disease in multiple myeloma: state of the art WB-MRI and PET/CT
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DOI: 10.1007/s00256-021-03841-5
Abstract: Bone imaging has been intimately associated with the diagnosis and staging of multiple myeloma (MM) for more than 5 decades, as the presence of bone lesions indicates advanced disease and dictates treatment initiation. The methods… read more here.
Keywords: minimal residual; response; treatment; disease ... See more keywords
Achieving minimal residual disease-negative by multiparameter flow cytometry may ameliorate a poor prognosis in MM patients with high-risk cytogenetics: a retrospective single-center analysis
Sign Up to like & getrecommendations! Published in 2019 at "Annals of Hematology"
DOI: 10.1007/s00277-019-03609-x
Abstract: The aim of our study was to evaluate the prognostic impact of minimal residual disease (MRD) and high-risk cytogenetics (HRCs) on outcomes in multiple myeloma (MM) patients. We applied multiparameter flow cytometry (MFC) to detect… read more here.
Keywords: pfs; risk; minimal residual; mrd ... See more keywords
Clinical value of minimal residual disease assessed by multiparameter flow cytometry in amyloid light chain amyloidosis
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Cancer Research and Clinical Oncology"
DOI: 10.1007/s00432-021-03653-z
Abstract: To assess the feasibility and prognostic value of minimal residual disease (MRD) evaluated by multiparameter flow cytometry (MFC) in newly diagnosed amyloid light chain (AL) amyloidosis. Clinical data from 25 consecutive newly diagnosed AL amyloidosis… read more here.
Keywords: value minimal; minimal residual; residual disease; amyloidosis ... See more keywords