TREK-1 and TREK-2 knockout mice are not resistant to halothane or isoflurane.
Sign Up to like & getrecommendations! Published in 2023 at "Anesthesiology"
DOI: 10.1097/aln.0000000000004577
Abstract: Background: A variety of molecular targets for volatile anesthetics have been suggested, including the anesthetic-sensitive potassium leak channel, TREK-1. Knockout of TREK-1 is reported to render mice resistant to volatile anesthetics, making TREK-1 channels compelling… read more here.
Keywords: minimum alveolar; isoflurane; halothane; trek trek ... See more keywords
Influence of Minimum Alveolar Concentration and Inhalation Duration of Sevoflurane on Facial Nerve Electromyography in Hemifacial Spasm: A Randomized Controlled Trial.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of neurosurgical anesthesiology"
DOI: 10.1097/ana.0000000000000848
Abstract: BACKGROUND The lateral spread response (LSR) is an electromyography feature of hemifacial spasm; intraoperative reduction in the LSR is associated with positive surgical outcomes. This study examined the effects of different minimum alveolar concentrations (MACs)… read more here.
Keywords: hemifacial spasm; minimum alveolar; sevoflurane; lsr ... See more keywords
Effects of sevoflurane and desflurane on the nociceptive responses of substantia gelatinosa neurons in the rat spinal cord dorsal horn: An in vivo patch-clamp analysis
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DOI: 10.1177/1744806920903149
Abstract: Background Volatile anesthetics suppress noxiously evoked activity in the spinal dorsal horn, which could contribute in part to analgesia, immobility. Modulation of excitatory and inhibitory synaptic transmission in substantia gelatinosa neurons could lead to the… read more here.
Keywords: substantia gelatinosa; sevoflurane desflurane; dorsal horn; postsynaptic currents ... See more keywords
Determination of the minimum alveolar concentration of isoflurane in donkeys.
Sign Up to like & getrecommendations! Published in 2022 at "American journal of veterinary research"
DOI: 10.2460/ajvr.21.12.0200
Abstract: OBJECTIVE To determine the minimum alveolar concentration (MAC) of isoflurane in donkeys and characterize recovery from anesthesia. ANIMALS 7 healthy castrated male adult donkeys. PROCEDURES Anesthesia was induced with propofol and maintained under mechanical ventilation… read more here.
Keywords: concentration; minimum alveolar; isoflurane; mac ... See more keywords
Effect of oral administration of gabapentin on the minimum alveolar concentration of isoflurane in cats
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Veterinary Science"
DOI: 10.3389/fvets.2023.1117313
Abstract: Objective To determine if oral gabapentin decreases the minimum alveolar concentration (MAC) of isoflurane in cats. Study design Prospective, randomized, blinded, crossover, and experimental study. Animals A total of six healthy adult cats (three male,… read more here.
Keywords: isoflurane cats; minimum alveolar; gabapentin; isoflurane ... See more keywords