Predictive Multivariate Linear Regression Analysis Guides Successful Catalytic Enantioselective Minisci Reactions of Diazines
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DOI: 10.1021/jacs.9b11658
Abstract: The Minisci reaction is one of the most direct and versatile methods for forging new carbon–carbon bonds onto basic heteroarenes: a broad subset of compounds ubiquitous in medicinal chemistry. While many Minisci-type reactions result in… read more here.
Keywords: linear regression; multivariate linear; analysis; minisci ... See more keywords
LiBr-promoted photoredox neutral Minisci hydroxyalkylations of quinolines with aldehydes
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DOI: 10.1039/d0gc01872d
Abstract: Photoredox-neutral hydroxyalkylations of quinolines with aldehydes, induced by sustainable visible light under mild conditions, are described. Non-toxic and inexpensive LiBr is found to be the key for the success of the atom-economical Minisci method. Combined… read more here.
Keywords: libr promoted; photoredox neutral; hydroxyalkylations quinolines; quinolines aldehydes ... See more keywords