LncRNA SNHG14 contributes to proinflammatory cytokine production in rheumatoid arthritis via the regulation of the miR-17-5p/MINK1-JNK pathway.
Sign Up to like & getrecommendations! Published in 2021 at "Environmental toxicology"
DOI: 10.1002/tox.23361
Abstract: Rheumatoid arthritis (RA) is a widespread autoimmune disorder of the joints. Long noncoding RNAs (lncRNAs) have been reported to participate in the pathogenesis of RA by serving as competitive endogenous RNAs. LncRNA small nucleolar RNA… read more here.
Keywords: mink1; mir; mir mink1; jnk pathway ... See more keywords
Dual roles of Misshapen/NIK-related kinase (MINK1) in osteoarthritis subtypes through the activation of TGFβ signaling.
Sign Up to like & getrecommendations! Published in 2019 at "Osteoarthritis and cartilage"
DOI: 10.1016/j.joca.2019.09.009
Abstract: OBJECTIVE To identify the role of misshapen/NIK-related kinase (MINK1) in age-related OA and injury-induced OA, and the effects of enhanced TGFβ signaling in these progresses. DESIGN The effect of MINK1 was analyzed with MINK1 knock… read more here.
Keywords: mink1; mink1 mice; tgf; misshapen nik ... See more keywords
Priming of NLRP3 inflammasome activation by Msn kinase MINK1 in macrophages
Sign Up to like & getrecommendations! Published in 2021 at "Cellular and Molecular Immunology"
DOI: 10.1038/s41423-021-00761-1
Abstract: The nucleotide-binding domain, leucine-rich-repeat containing family, pyrin domain-containing 3 (NLRP3) inflammasome is essential in inflammation and inflammatory disorders. Phosphorylation at various sites on NLRP3 differentially regulates inflammasome activation. The Ser725 phosphorylation site on NLRP3 is… read more here.
Keywords: mink1; inflammasome activation; activation; kinase mink1 ... See more keywords