Kinesin-14 motors participate in a force balance at microtubule plus-ends to regulate dynamic instability
Sign Up to like & getrecommendations! Published in 2022 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2108046119
Abstract: Significance Kinesin-14 motors represent an essential class of molecular motors that bind to microtubules and then walk toward the microtubule minus-end. However, whether these motors can interact with growing plus-ends of microtubules to impact the… read more here.
Keywords: kinesin motors; plus ends; microtubule plus; microtubule ... See more keywords
MCRS1 modulates the heterogeneity of microtubule minus-end morphologies in mitotic spindles
Sign Up to like & getrecommendations! Published in 2022 at "Molecular Biology of the Cell"
DOI: 10.1101/2022.06.03.494715
Abstract: Faithful chromosome segregation requires the assembly of a bipolar spindle, consisting of two antiparallel microtubule (MT) arrays having most of their minus ends focused at the spindle poles and their plus ends overlapping in the… read more here.
Keywords: end morphologies; heterogeneity; minus ends; microtubule ... See more keywords
CAMSAP2 Is a Microtubule Minus-End Targeting Protein That Regulates BTB Dynamics Through Cytoskeletal Organization.
Sign Up to like & getrecommendations! Published in 2019 at "Endocrinology"
DOI: 10.1210/en.2018-01097
Abstract: During spermatogenesis, microtubule (MT) cytoskeleton in Sertoli cells confers blood-testis barrier (BTB) function, but the regulators and mechanisms that modulate MT dynamics remain unexplored. In this study, we examined the role of calmodulin-regulated spectrin-associated protein… read more here.
Keywords: camsap2; protein; end; sertoli cell ... See more keywords