Differential expression of microRNAs let‐7a, miR‐125b, miR‐100, and miR‐21 and interaction with NF‐kB pathway genes in periodontitis pathogenesis
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.26391
Abstract: Periodontitis is a chronic inflammatory disease which is caused by destruction of the tissues that surrounds and supports the tooth. Deregulation of microRNAs has been reported to cause several inflammatory diseases such as autoimmune disease,… read more here.
Keywords: mir 125b; expression; let mir; mir 100 ... See more keywords
PLK1-associated microRNAs are correlated with pediatric medulloblastoma prognosis
Sign Up to like & getrecommendations! Published in 2017 at "Child's Nervous System"
DOI: 10.1007/s00381-017-3366-5
Abstract: PurposeMedulloblastoma (MB) is the most common malignant tumor of the central nervous system (CNS) in children. Despite its relative good survival rates, treatment can cause long time sequels and may impair patients’ lifespan and quality,… read more here.
Keywords: prognosis; mir; expression; mir 100 ... See more keywords
Clinical significance and oncogene function of long noncoding RNA HAGLROS overexpression in ovarian cancer
Sign Up to like & getrecommendations! Published in 2019 at "Archives of Gynecology and Obstetrics"
DOI: 10.1007/s00404-019-05218-5
Abstract: PurposeTo explore the clinical significance and mechanism of long noncoding RNA (lncRNA) HAGLROS in ovarian cancer.MethodsThe expression of HAGLROS in ovarian cancer was verified by online databases and quantitative reverse transcription polymerase chain reaction (qRT-PCR),… read more here.
Keywords: long noncoding; noncoding rna; clinical significance; ovarian cancer ... See more keywords
Differentially expressed miR-20, miR-21, miR-100, miR-125a and miR-146a as a potential biomarker for prostate cancer.
Sign Up to like & getrecommendations! Published in 2021 at "Molecular biology reports"
DOI: 10.1007/s11033-021-06384-z
Abstract: Prostate cancer is the leading cause of death among men worldwide. Deregulation of microRNAs has been reported in many cancers. Expression of microRNAs miR-20a-5p, miR-21-5p, miR-100-5p, miR-125a-5p and miR-146a-5p in tissue blocks of histologically confirmed… read more here.
Keywords: mir mir; mir 100; mir; prostate cancer ... See more keywords
Engineered Extracellular Vesicles Loaded with MiR-100-5p Antagonist Selectively Target the Lesioned Region to Promote Recovery from Brain Damage
Sign Up to like & getrecommendations! Published in 2025 at "Neuroscience Bulletin"
DOI: 10.1007/s12264-025-01376-6
Abstract: Hypoxic-ischemic (HI) brain damage poses a high risk of death or lifelong disability, yet effective treatments remain elusive. Here, we demonstrated that miR-100-5p levels in the lesioned cortex increased after HI insult in neonatal mice.… read more here.
Keywords: extracellular vesicles; mir 100; brain; engineered extracellular ... See more keywords
Long non-coding RNA HAGLROS facilitates the malignant phenotypes of NSCLC cells via repressing miR-100 and up-regulating SMARCA5
Sign Up to like & getrecommendations! Published in 2020 at "Biomedical journal"
DOI: 10.1016/j.bj.2020.12.008
Abstract: Abstract Background Long non-coding RNA (lncRNA) is implicated in the progression of multiple cancers. This study aimed to explore the expression characteristics, biological function and molecular mechanism of lncRNA HAGLROS expression in NSCLC. Methods Quantitative… read more here.
Keywords: phenotypes nsclc; nsclc cells; smarca5; expression ... See more keywords
miR-100-5p inhibition induces apoptosis in dormant prostate cancer cells and prevents the emergence of castration-resistant prostate cancer
Sign Up to like & getrecommendations! Published in 2017 at "Scientific Reports"
DOI: 10.1038/s41598-017-03731-8
Abstract: Carcinoma of the prostate is the most common cancer in men. Treatment of aggressive prostate cancer involves a regiment of radical prostectomy, radiation therapy, chemotherapy and hormonal therapy. Despite significant improvements in the last decade,… read more here.
Keywords: therapy; prostate cancer; castration resistant; cancer ... See more keywords
miR-100-5p in human umbilical cord mesenchymal stem cell-derived exosomes mediates eosinophilic inflammation to alleviate atherosclerosis via the FZD5/Wnt/β-catenin pathway.
Sign Up to like & getrecommendations! Published in 2021 at "Acta biochimica et biophysica Sinica"
DOI: 10.1093/abbs/gmab093
Abstract: Exosomes derived from human umbilical cord mesenchymal stem cells (hUMSC-Ex) play important roles in immune and inflammation diseases. However, the role of hUMSC-Ex in atherosclerosis has not been elucidated. In this study, the isolated exosomes… read more here.
Keywords: inflammation; atherosclerosis; mir 100; cell ... See more keywords
NF-κB/Relish readjusts miR-100 expression and recovers immune homeostasis in Drosophila melanogaster.
Sign Up to like & getrecommendations! Published in 2024 at "Insect science"
DOI: 10.1111/1744-7917.13484
Abstract: The regulation and maintenance of immune homeostasis are essential for animal survival, but the molecular mechanisms are not fully understood. Here, we used the model organism Drosophila melanogaster to uncover a potential mechanism by which… read more here.
Keywords: expression; mir 100; immune homeostasis; drosophila melanogaster ... See more keywords
METTL14 affects UVB‐induced human dermal fibroblasts photoaging via miR‐100‐3p biogenesis in an m6A‐dependent manner
Sign Up to like & getrecommendations! Published in 2024 at "Aging Cell"
DOI: 10.1111/acel.14123
Abstract: Exposure to ultraviolet radiation can lead to skin photoaging, which increases the risk of skin tumors. This study aims to investigate how microRNA m6A modification contributes to skin photoaging. This study found that skin fibroblasts… read more here.
Keywords: mir 100; m6a dependent; m6a; mettl14 ... See more keywords
Downregulation of microRNA‐100/microRNA‐125b is associated with lymph node metastasis in early colorectal cancer with submucosal invasion
Sign Up to like & getrecommendations! Published in 2017 at "Cancer Science"
DOI: 10.1111/cas.13152
Abstract: A majority of early colorectal cancers (CRCs) with submucosal invasion undergo surgical operation, despite a very low incidence of lymph node metastasis. Our study aimed to identify microRNAs (miRNAs) specifically responsible for lymph node metastasis… read more here.
Keywords: node metastasis; invasion; metastasis; lymph node ... See more keywords