Circular RNA Derived from Vacuolar ATPase Assembly Factor VMA21 Suppresses Lipopolysaccharide-Induced Apoptosis of Chondrocytes in Osteoarthritis (OA) by Decreasing Mature miR-103 Production
Sign Up to like & getrecommendations! Published in 2022 at "Molecular Biotechnology"
DOI: 10.1007/s12033-022-00451-x
Abstract: Circular RNA derived from vacuolar ATPase assembly factor (VMA21) has been proven to be an inflammation suppressor in many diseases, while its role in osteoarthritis (OA) is unknown. We predicted that VMA21 participates in OA… read more here.
Keywords: mir 103; apoptosis; mature mir; vma21 ... See more keywords
Long non-coding RNA TP73‑AS1 promotes colorectal cancer proliferation by acting as a ceRNA for miR‑103 to regulate PTEN expression.
Sign Up to like & getrecommendations! Published in 2019 at "Gene"
DOI: 10.1016/j.gene.2018.11.072
Abstract: There is an increasing evidence that long non-coding RNAs (lncRNAs) play an important role in tumorigenesis and cancer progression. This study focused on the functional role of P73 antisense RNA 1T (TP73‑AS1), a lncRNA, in… read more here.
Keywords: tp73 as1; mir 103; pten expression; crc ... See more keywords
Inhibition of miR-103-3p Preserves Neurovascular Integrity Through Caveolin-1 in Experimental Subarachnoid Hemorrhage
Sign Up to like & getrecommendations! Published in 2021 at "Neuroscience"
DOI: 10.1016/j.neuroscience.2021.03.007
Abstract: Caveolin-1 (Cav-1) is a constitutive structural protein of caveolae in the plasma membrane. It plays an important role in maintaining blood brain barrier (BBB) integrity. In this study, we identified that miR-103-3p, a hypoxia-responsive miRNA,… read more here.
Keywords: mir 103; inhibition mir; subarachnoid hemorrhage; integrity ... See more keywords
LncRNA BC083743 Promotes the Proliferation of Schwann Cells and Axon Regeneration Through miR-103-3p/BDNF After Sciatic Nerve Crush.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of neuropathology and experimental neurology"
DOI: 10.1093/jnen/nlaa069
Abstract: To investigate the underlying mechanism of lncRNA BC083743 in regulating the proliferation of Schwann cells (SCs) and axon regeneration after sciatic nerve crush (SNC), we used a rat model. Sciatic function index and the atrophy… read more here.
Keywords: mir 103; axon regeneration; proliferation; bc083743 ... See more keywords
Changes in miroRNA‐103 expression in wound margin tissue are related to wound healing of diabetes foot ulcers
Sign Up to like & getrecommendations! Published in 2022 at "International Wound Journal"
DOI: 10.1111/iwj.13895
Abstract: To investigate the relationship between small noncoding microRNA‐103 (miR‐103) and wound healing of diabetic foot ulcers (DFU) and the underlying molecular mechanism, forty type 2 diabetes mellitus with DFU (DFU group), and 20 patients with… read more here.
Keywords: 103 expression; wound healing; foot ulcers; expression ... See more keywords
Diagnostic Value of miR-103 in Patients with Sepsis and Noninfectious SIRS and Its Regulatory Role in LPS-Induced Inflammatory Response by Targeting TLR4
Sign Up to like & getrecommendations! Published in 2020 at "International Journal of Genomics"
DOI: 10.1155/2020/2198308
Abstract: Background Sepsis is a life-threatening condition and a systemic inflammatory response syndrome (SIRS) driven by infection. This study aimed at investigating the expression of microRNA-103 (miR-103) in sepsis patients, evaluating its diagnostic value, and exploring… read more here.
Keywords: sepsis; mir 103; inflammatory response; value ... See more keywords
LncRNA-GAS5 Inhibits Expression of miR 103 and Ameliorates the Articular Cartilage in Adjuvant-Induced Arthritis in Obese Mice
Sign Up to like & getrecommendations! Published in 2020 at "Dose-Response"
DOI: 10.1177/1559325820942718
Abstract: We explored whether long noncoding RNA growth arrest-specific transcript 5 (LncRNA-GAS5) small interfering RNA (siRNA) reduced cartilage destruction in obese mice with adjuvant-induced arthritis. We studied the effects of LncRNA-GAS5 siRNA on the polyarthritis index;… read more here.
Keywords: mir 103; expression; sirna; lncrna gas5 ... See more keywords
miR-103/107 promote ER stress-mediated apoptosis via targeting the Wnt3a/β-catenin/ATF6 pathway in preadipocytes
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Lipid Research"
DOI: 10.1194/jlr.m082602
Abstract: Both miR-103 and miR-107 have been demonstrated to restrain cell proliferation and regulate lipid metabolism and inflammation. However, the effects of miR-103/107 on preadipocyte apoptosis remain unknown. In the present research, we have investigated how… read more here.
Keywords: stress mediated; mir 103; 103 107; mediated apoptosis ... See more keywords
Effects of miR-103 by negatively regulating SATB2 on proliferation and osteogenic differentiation of human bone marrow mesenchymal stem cells
Sign Up to like & getrecommendations! Published in 2020 at "PLoS ONE"
DOI: 10.1371/journal.pone.0232695
Abstract: Background The proliferation and osteogenic differentiation of human bone marrow mesenchymal stem cells (HBMScs) are modulated by a variety of microRNAs (miRNAs). SATB homeobox 2 (SATB2) is a critical transcription factor that contributes to maintain… read more here.
Keywords: proliferation osteogenic; mir 103; osteogenic differentiation; satb2 ... See more keywords
miR-103 inhibits proliferation and sensitizes hemopoietic tumor cells for glucocorticoid-induced apoptosis
Sign Up to like & getrecommendations! Published in 2017 at "Oncotarget"
DOI: 10.18632/oncotarget.13447
Abstract: Glucocorticoid (GC) hormones are an important ingredient of leukemia therapy since they are potent inducers of lymphoid cell apoptosis. However, the development of GC resistance remains an obstacle in GC-based treatment. In the present investigation… read more here.
Keywords: mir 103; apoptosis; induced apoptosis; inhibits proliferation ... See more keywords
Regulatory effect of MiR103 on proliferation, EMT and invasion of oral squamous carcinoma cell through SALL4.
Sign Up to like & getrecommendations! Published in 2019 at "European review for medical and pharmacological sciences"
DOI: 10.26355/eurrev_201911_19559
Abstract: OBJECTIVE Oral squamous cell carcinoma (OSCC) is a common tumor of head and neck cancer. MiR-103 is involved in several tumors. However, the role and mechanism of miR103 in OSCC remain unclear. MATERIALS AND METHODS… read more here.
Keywords: mir 103; invasion; oral squamous; proliferation ... See more keywords