Articles with "mir 103a" as a keyword



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hsa_circ_0062389 promotes the progression of non-small cell lung cancer by sponging miR-103a-3p to mediate CCNE1 expression.

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Published in 2019 at "Cancer genetics"

DOI: 10.1016/j.cancergen.2019.12.004

Abstract: Recently, increasing evidence showed that circular RNAs (circRNAs) play critical roles in tumor progression. However, the roles of hsa_circ_0062389 in non-small cell lung cancer (NSCLC) development remain unclear. In the present study, hsa_circ_0062389 expression was… read more here.

Keywords: circ 0062389; ccne1; mir 103a; lung cancer ... See more keywords
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Berberine represses Wnt/β-catenin pathway activation via modulating the microRNA-103a-3p/Bromodomain-containing protein 4 axis, thereby refraining pyroptosis and reducing the intestinal mucosal barrier defect induced via colitis

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Published in 2022 at "Bioengineered"

DOI: 10.1080/21655979.2022.2047405

Abstract: ABSTRACT Intestinal barrier dysfunction is inflammatory bowel disease’s hallmark. Berberine (BBR) has manifested its anti-inflammatory properties in colitis. For exploring the molecular mechanism of BBR’s impacts on colitis, application of a dextran sodium sulfate-induced mouse… read more here.

Keywords: mucosal barrier; barrier; mir 103a; colitis ... See more keywords
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Role of MicroRNA-103a Targeting ADAM10 in Abdominal Aortic Aneurysm

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Published in 2017 at "BioMed Research International"

DOI: 10.1155/2017/9645874

Abstract: MicroRNAs (miRNAs) are deregulated in various vascular ailments including abdominal aortic aneurysm (AAA). MiR-103 is involved in vascular, metabolic, and malignant diseases, but whether it participates in the pathogenesis of AAA remains elusive. ADAM10 plays… read more here.

Keywords: mir 103a; aortic aneurysm; expression; expression adam10 ... See more keywords
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Dexmedetomidine Mitigates Microglial Activation Associated with Postoperative Cognitive Dysfunction by Modulating the MicroRNA-103a-3p/VAMP1 Axis

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Published in 2022 at "Neural Plasticity"

DOI: 10.1155/2022/1353778

Abstract: Surgery-induced microglial activation is critical in mediating postoperative cognitive dysfunction (POCD) in elderly patients, where the important protective effect of dexmedetomidine has been indicated. However, the mechanisms of action of dexmedetomidine during the neuroinflammatory response… read more here.

Keywords: 103a vamp1; microglial activation; mir 103a; postoperative cognitive ... See more keywords
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Dysregulation of miR-103a Mediates Cigarette Smoking Induced Lipid-laden Macrophage Formation.

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Published in 2022 at "American journal of respiratory cell and molecular biology"

DOI: 10.1165/rcmb.2022-0202oc

Abstract: Cigarette smoke (CS) is considered a major risk factor for chronic obstructive pulmonary disease (COPD), which is currently the third leading cause of death in the United States. Studies have indicated that COPD patients have… read more here.

Keywords: macrophage formation; laden macrophage; induced lipid; mir 103a ... See more keywords
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Linc00152 promotes malignant progression of glioma stem cells by regulating miR-103a-3p/FEZF1/CDC25A pathway

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Published in 2017 at "Molecular Cancer"

DOI: 10.1186/s12943-017-0677-9

Abstract: BackgroundGlioma is one of the most frequent intracranial malignant tumors. LncRNAs have been identified as new modulators in the origination and progression of glioma.MethodsQuantitative real-time PCR were conducted to evaluate the expression of linc00152 and… read more here.

Keywords: mir 103a; fezf1 cdc25a; expression; glioma ... See more keywords
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MIR503HG Overexpression Inhibits the Malignant Behaviors of Osteosarcoma Cells by Sponging miR-103a-3p.

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Published in 2023 at "Critical reviews in eukaryotic gene expression"

DOI: 10.1615/critreveukaryotgeneexpr.2022042373

Abstract: Osteosarcoma (OS) is the most representative primary bone tumour in children and teenagers. This study explored the regulatory effects of long noncoding RNA MIR503HG (MIR503HG) on the biological functions of OS cells, and further investigated… read more here.

Keywords: mir503hg; mir 103a; malignant behaviors; expression mir503hg ... See more keywords
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miR-103a-3p and miR-22-5p Are Reliable Reference Genes in Extracellular Vesicles From Cartilage, Adipose Tissue, and Bone Marrow Cells

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Published in 2021 at "Frontiers in Bioengineering and Biotechnology"

DOI: 10.3389/fbioe.2021.632440

Abstract: Cartilage cells (CCs), adipose tissue (ASC)- and bone marrow (BMSC)-derived mesenchymal stromal cells (MSCs) have been shown as promising candidates for the treatment of osteoarthritis (OA). Despite their adaptive ability, exposure to chronic catabolic and… read more here.

Keywords: extracellular vesicles; mir 103a; mir; 103a mir ... See more keywords
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Effects of miR-103a-3p Targeted Regulation of TRIM66 Axis on Docetaxel Resistance and Glycolysis in Prostate Cancer Cells

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Published in 2022 at "Frontiers in Genetics"

DOI: 10.3389/fgene.2021.813793

Abstract: Objective: We aimed to study the expressions of miR-103a-3p and TRIM66 in prostate cancer (PCa) cells, explore the direct target genes of miR-103a-3p, and analyze the effects of miR-103a-3p targeted regulation of the TRIM66 axis… read more here.

Keywords: mir 103a; trim66; glycolysis; resistance ... See more keywords
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Two oncomiRs, miR-182-5p and miR-103a-3p, Involved in Intravenous Leiomyomatosis

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Published in 2023 at "Genes"

DOI: 10.3390/genes14030712

Abstract: Leiomyomas, also referred to as fibroids, belong to the most common type of benign tumors developing in the myometrium of the uterus. Intravenous leiomyomatosis (IVL) tends to be regarded as a rare type of uterine… read more here.

Keywords: leiomyomatosis; intravenous leiomyomatosis; group; mir 103a ... See more keywords
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The Relationship between Serum Adipokines, miR-222-3p, miR-103a-3p and Glucose Regulation in Pregnancy and Two to Three Years Post-Delivery in Women with Gestational Diabetes Mellitus Adhering to Mediterranean Diet Recommendations

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Published in 2022 at "Nutrients"

DOI: 10.3390/nu14224712

Abstract: The San Carlos Gestational Diabetes Mellitus (GDM) prevention study, a nutritional intervention RCT based on a Mediterranean Diet (MedDiet), has been shown to reduce the incidence of GDM. The objective of this study is to… read more here.

Keywords: 222 mir; mir 103a; visit; mir ... See more keywords