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   Articles with "mir 106a" as a keyword



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LINC00657 activates PD-L1 to promote osteosarcoma metastasis via miR-106a.

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recommendations! Published in 2020 at "Journal of cellular biochemistry"

DOI: 10.1002/jcb.29574

Abstract: Osteosarcoma (OS) cells are one of the primary cancer-related causes of death around the world. Long noncoding RNAs are key for OS progression; however, the detailed molecular mechanism remains unknown. LINC00657, miR-106a, and programmed death… read more here.

Keywords: linc00657; metastasis; vessel formation; linc00657 activates ... See more keywords
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MicroRNA-106a-5p alleviated the resistance of cisplatin in lung cancer cells by targeting Jumonji domain containing 6.

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recommendations! Published in 2021 at "Transplant immunology"

DOI: 10.1016/j.trim.2021.101478

Abstract: BACKGROUND Cisplatin (DDP) is used for lung cancer therapy. MicroRNAs, small non-coding RNAs, may contribute to tumorigenesis as well as to drug resistance. We examined regulatory functions of miR-106a-5p in DDP-resistant lung cancer cells. METHODS… read more here.

Keywords: lung cancer; ddp; mir 106a; apoptosis ... See more keywords
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miR-106a deficiency attenuates inflammation in murine IBD models.

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recommendations! Published in 2018 at "Mucosal immunology"

DOI: 10.1038/s41385-018-0091-7

Abstract: Pro-inflammatory cytokine TNFα antagonizes regulatory T cell (Treg) suppressive function with a measurable reduction of IL-10 protein secretion. Tregs are critical to suppress excessive immune activation, particularly within the intestine where high antigenic loads elicit… read more here.

Keywords: murine; ibd; suppressive function; deficiency ... See more keywords
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Long non-coding RNA GASL1 restrains gastric carcinoma cell proliferation and metastasis by sponging microRNA-106a

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recommendations! Published in 2020 at "Cell Cycle"

DOI: 10.1080/15384101.2020.1812918

Abstract: ABSTRACT Background: Gastric carcinoma (GC) is a common malignant tumor. Recently, it has been found that long non-coding RNAs (lncRNAs) play important role in cancer. In this paper, we investigated the effects and mechanism of… read more here.

Keywords: cell proliferation; gasl1; metastasis; cell ... See more keywords
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Lymphoma cell-derived extracellular vesicles inhibit autophagy and apoptosis to promote lymphoma cell growth via the microRNA-106a/Beclin1 axis

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recommendations! Published in 2022 at "Cell Cycle"

DOI: 10.1080/15384101.2022.2047335

Abstract: ABSTRACT Lymphoma is a common malignant tumor globally. Tumor-derived extracellular vesicles (Evs) participate in genetic information exchange between tumor cells. We investigated the role and mechanism of human Burkitt lymphoma cells Raji-derived Evs (Raji-Evs) in… read more here.

Keywords: cell; lymphoma; autophagy apoptosis; mir 106a ... See more keywords

MicroRNA miR-106a-5p targets forkhead box transcription factor FOXC1 to suppress the cell proliferation, migration, and invasion of ectopic endometrial stromal cells via the PI3K/Akt/mTOR signaling pathway.

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recommendations! Published in 2021 at "Bioengineered"

DOI: 10.1080/21655979.2021.1933679

Abstract: Emerging evidence has exhibited an obvious decreased expression of miR-106a-5p in the ectopic endometrial tissue of endometriosis (EMS) patients. Thus far, the pathophysiological function of miR-106a-5p in EMS is unknown. A previous study showed an… read more here.

Keywords: pi3k; foxc1; endometrial stromal; ectopic endometrial ... See more keywords
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HOTAIR mediates cisplatin resistance in nasopharyngeal carcinoma by regulating miR-106a-5p/SOX4 axis

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recommendations! Published in 2022 at "Bioengineered"

DOI: 10.1080/21655979.2022.2038429

Abstract: ABSTRACT This study explored the function and mechanisms of HOX transcript antisense RNA (HOTAIR) in the drug resistance of nasopharyngeal carcinoma (NPC). Quantitative PCR, Western blotting, MTT assay, flow cytometry, Transwell assay, and luciferase assay… read more here.

Keywords: resistance nasopharyngeal; mir 106a; expression; sox4 ... See more keywords
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MiR-106a facilitates the sensorineural hearing loss induced by oxidative stress by targeting connexin-43

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recommendations! Published in 2022 at "Bioengineered"

DOI: 10.1080/21655979.2022.2071021

Abstract: ABSTRACT Sensorineural hearing loss (SNHL) is a common clinical side effect resulted from the overusing of aminoglycoside antibacterial drugs, such as gentamicin. Oxidative stress is recently evidenced to be an important inducer for SNHL, which… read more here.

Keywords: snhl; mir 106a; oxidative stress; connexin ... See more keywords
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CeRNA network identified hsa-miR-17-5p, hsa-miR-106a-5p and hsa-miR-2355-5p as potential diagnostic biomarkers for tuberculosis

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recommendations! Published in 2023 at "Medicine"

DOI: 10.1097/md.0000000000033117

Abstract: This study aims to analyze the regulatory non-coding RNAs in the pathological process of tuberculosis (TB), and identify novel diagnostic biomarkers. A longitudinal study was conducted in 5 newly diagnosed pulmonary tuberculosis patients, peripheral blood… read more here.

Keywords: mir 106a; hsa; hsa mir; diagnostic biomarkers ... See more keywords
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Exosomal miR‐106a‐5p accelerates the progression of nasopharyngeal carcinoma through FBXW7‐mediated TRIM24 degradation

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recommendations! Published in 2022 at "Cancer Science"

DOI: 10.1111/cas.15337

Abstract: Nasopharyngeal carcinoma (NPC) is prevalent in East Asia and causes increased health burden. Elucidating the regulatory mechanism of NPC progression is important for understanding the pathogenesis of NPC and developing novel therapeutic strategies. Nasopharyngeal carcinoma… read more here.

Keywords: nasopharyngeal carcinoma; fbxw7; mir 106a; exosomal mir ... See more keywords
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The MicroRNA-106a/20b Strongly Enhances the Antitumour Immune Responses of Dendritic Cells Pulsed with Glioma Stem Cells by Targeting STAT3

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recommendations! Published in 2022 at "Journal of Immunology Research"

DOI: 10.1155/2022/9721028

Abstract: Background Evaluate the effect of the miRNA-106a/20b on the efficacy of DCs pulsed with GSCs in activating GSC-specific T cell responses. Methods We cultured GSCs and prepared GSC antigen lysates by apoptosis. Then, immature DCs… read more here.

Keywords: 106a 20b; antitumour immune; immune responses; mir 106a ... See more keywords