miR-107 regulates the effect of MCM7 on the proliferation and apoptosis of colorectal cancer via the PAK2 pathway.
Sign Up to like & getrecommendations! Published in 2021 at "Biochemical pharmacology"
DOI: 10.1016/j.bcp.2021.114610
Abstract: Microchromosome maintenance protein 7 (MCM7), a DNA replication permitting factor, plays an essential role in initiating DNA replication. MCM7 is reported to be involved in tumor formation and progression, whereas the expression profile and molecular… read more here.
Keywords: mir 107; colorectal cancer; proliferation; crc ... See more keywords
Therapeutic potential of synthetic microRNA mimics based on the miR-15/107 consensus sequence
Sign Up to like & getrecommendations! Published in 2025 at "Cancer Gene Therapy"
DOI: 10.1038/s41417-025-00885-w
Abstract: MicroRNA expression is frequently suppressed in cancer, and previously we demonstrated coordinate downregulation of multiple related microRNAs of the miR-15/107 group in malignant pleural mesothelioma (PM). From an alignment of the miR-15 family and the… read more here.
Keywords: consensus; therapeutic potential; mimics based; mir 107 ... See more keywords
MicroRNA-107 enhances radiosensitivity by suppressing granulin in PC-3 prostate cancer cells
Sign Up to like & getrecommendations! Published in 2020 at "Scientific Reports"
DOI: 10.1038/s41598-020-71128-1
Abstract: Prostate cancer is the second leading cause of cancer-related death worldwide. Radiotherapy is often applied for the treatment, but radioresistance is a challenge in some patients. MicroRNAs have been reported to be involved in the… read more here.
Keywords: radiosensitivity; mir 107; prostate cancer; cancer ... See more keywords
P53/PANK1/miR‐107 signalling pathway spans the gap between metabolic reprogramming and insulin resistance induced by high‐fat diet
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Cellular and Molecular Medicine"
DOI: 10.1111/jcmm.15053
Abstract: High‐fat diet (HFD) leads to obesity, type II diabetes mellitus (T2DM) and increases the coincidence of cardiovascular diseases and cancer. Insulin resistance (IR) is considered as the ‘common soil’ of those diseases. Furthermore, people on… read more here.
Keywords: pank1 mir; metabolic reprogramming; mir 107; high fat ... See more keywords
Circ_0001971 makes progress of oral squamous cell carcinoma by targeting miR-107/FZD4 axis.
Sign Up to like & getrecommendations! Published in 2022 at "Oral diseases"
DOI: 10.1111/odi.14207
Abstract: BACKGROUND Accumulating articles have suggested the important regulatory roles of circular RNAs (circRNAs) in human cancers, including oral squamous cell carcinoma (OSCC). However, the role of circ_0001971 in OSCC progression remains to be determined. METHODS… read more here.
Keywords: cell; mir 107; fzd4; circ 0001971 ... See more keywords
LINC-DUBR Suppresses Malignant Progression of Ovarian Cancer by Downregulating miR-107 to Induce SMAC Expression
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Healthcare Engineering"
DOI: 10.1155/2022/4535655
Abstract: Background LINC-DUBR may be a potential therapeutic target in ovarian cancer (OC). The purpose of this research was to explore the impact of miR-107 on the tumorigenicity of OC and its underlying molecular mechanisms. Methods… read more here.
Keywords: mir 107; ovarian cancer; linc dubr;
miR-107 modulates EMT progression of OSCC by targeting SNCG and inhibiting the ERK/NF-κB signaling pathways
Sign Up to like & getrecommendations! Published in 2025 at "Journal of Translational Medicine"
DOI: 10.1186/s12967-025-06910-8
Abstract: Oral squamous cell carcinoma (OSCC) is marked by aggressive metastasis and poor prognosis, with epithelial-mesenchymal transition (EMT) serving as a pivotal process in tumor metastasis. Consequently, identifying critical targets and elucidating the underlying mechanisms that… read more here.
Keywords: mir 107; migration invasion; sncg; emt progression ... See more keywords
hsa_circ_0020093 suppresses ovarian cancer progression by modulating LRPPRC activity and miR-107/LATS2 signaling
Sign Up to like & getrecommendations! Published in 2024 at "Biology Direct"
DOI: 10.1186/s13062-024-00520-y
Abstract: A substantive body of evidence has demonstrated the significant roles of circular RNA (circRNA) in cancer. However, the contribution of dysregulated circRNAs to ovarian cancer (OC) remains elusive. We aim to elucidate the critical roles… read more here.
Keywords: hsa circ; lats2; circ 0020093; mir 107 ... See more keywords
MiRNA-107 enhances the malignant progression of pancreatic cancer by targeting TGFBR3
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DOI: 10.1371/journal.pone.0249375
Abstract: Background The prognosis of pancreatic cancer (PC) is relatively dismal due to the lack of effective therapy. In this study, we explored the specific functions and molecular mechanisms of miR-107 to uncover effective therapeutic targets… read more here.
Keywords: 107 enhances; mir 107; targeting tgfbr3; mirna 107 ... See more keywords
MiR-107 inhibits the malignant biological behavior of esophageal squamous cell carcinoma by targeting TPM3
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Gastrointestinal Oncology"
DOI: 10.21037/jgo-22-575
Abstract: Background Esophageal squamous cell carcinoma (ESCC) is a highly lethal and aggressive tumor. Our previous study revealed that tropomyosin 3 (TPM3) is up-regulated in the late stage of ESCC and promotes epithelial-mesenchymal transition (EMT) via… read more here.
Keywords: tpm3; mir 107; squamous cell; expression ... See more keywords
High expression of miR-107 and miR-17 predicts poor prognosis and guides treatment selection in acute myeloid leukemia
Sign Up to like & getrecommendations! Published in 2023 at "Translational Cancer Research"
DOI: 10.21037/tcr-22-2484
Abstract: Background The prognostic significance of miR-107 and miR-17 in patients with acute myeloid leukemia (AML) remains unclear. Methods A total of 173 patients with de novo AML from the Cancer Genome Atlas database were enrolled… read more here.
Keywords: high mir; 107 mir; mir 107; expression ... See more keywords