miR‐124‐3p availability is antagonized by LncRNA‐MALAT1 for Slug‐induced tumor metastasis in hepatocellular carcinoma
Sign Up to like & getrecommendations! Published in 2019 at "Cancer Medicine"
DOI: 10.1002/cam4.2482
Abstract: As an oncogene, long noncoding RNA metastasis‐associated lung adenocarcinoma transcript 1 (MALAT1) can promote tumor metastasis. Hyperexpression of MALAT1 has been observed in many malignant tumors, including hepatocellular carcinoma (HCC). However, the role and mechanism… read more here.
Keywords: metastasis; tumor metastasis; hepatocellular carcinoma; mir 124 ... See more keywords
LINC00240 promotes gastric cancer cell proliferation, migration and EMT via the miR‐124‐3p / DNMT3B axis
Sign Up to like & getrecommendations! Published in 2020 at "Cell Biochemistry and Function"
DOI: 10.1002/cbf.3551
Abstract: Gastric cancer (GC) remains one of prevalent causes of cancer‐related deaths worldwide. Long noncoding RNA is related to various cancers. Our study was conducted to explore the biological effects of LINC00240 on the tumorigenesis of… read more here.
Keywords: 124 dnmt3b; linc00240; dnmt3b axis; mir 124 ... See more keywords
Imatinib suppresses activation of hepatic stellate cells by targeting STAT3/IL‐6 pathway through miR‐124
Sign Up to like & getrecommendations! Published in 2023 at "Cell Biology International"
DOI: 10.1002/cbin.11992
Abstract: The activation of hepatic stellate cells is the primary function of facilitating liver fibrosis. Interfering with the coordinators of different signaling pathways in activated hepatic stellate cells (aHSCs) could be a potential approach in ameliorating… read more here.
Keywords: imatinib; liver fibrosis; mir 124; stat3 ... See more keywords
microRNA‐124 regulates Notch and NeuroD1 to mediate transition states of neuronal development
Sign Up to like & getrecommendations! Published in 2022 at "Developmental Neurobiology"
DOI: 10.1002/dneu.22902
Abstract: MicroRNAs regulate gene expression by destabilizing target mRNA and/or inhibiting translation in animal cells. The ability to mechanistically dissect miR‐124′s function during specification, differentiation, and maturation of neurons during development within a single system has… read more here.
Keywords: regulates notch; mir 124; development; 124 regulates ... See more keywords
LAMC1 mRNA promotes malignancy of hepatocellular carcinoma cells by competing for MicroRNA‐124 binding with CD151
Sign Up to like & getrecommendations! Published in 2017 at "IUBMB Life"
DOI: 10.1002/iub.1642
Abstract: Specific RNAs can function as sinks for endogenous miRNAs, known as competing endogenous RNAs (ceRNAs). Here, we confirm a miR‐124 mediated ceRNA crosstalk between LAMC1 and CD151 in hepatocellular carcinoma (HCC). miR‐124 negatively regulates LAMC1… read more here.
Keywords: hepatocellular carcinoma; 124 binding; lamc1 mrna; cd151 ... See more keywords
LncRNA UCA1/miR‐124 axis modulates TGFβ1‐induced epithelial‐mesenchymal transition and invasion of tongue cancer cells through JAG1/Notch signaling
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.28334
Abstract: Tongue cancer remains a massive threat to public health due to the high rate of metastasis. Tumor cell epithelial‐mesenchymal transition (EMT), which can be induced by transforming growth factor β1 (TGFβ1), has been regarded as… read more here.
Keywords: invasion; tongue cancer; tgf induced; cancer ... See more keywords
miR-124-3p is a chronic regulator of gene expression after brain injury
Sign Up to like & getrecommendations! Published in 2018 at "Cellular and Molecular Life Sciences"
DOI: 10.1007/s00018-018-2911-z
Abstract: Traumatic brain injury (TBI) initiates molecular and cellular pathologies that underlie post-injury morbidities, including hippocampus-related memory decline and epileptogenesis. Non-coding small RNAs are master regulators of gene expression with the potential to affect multiple molecular… read more here.
Keywords: gene expression; tbi; mir 124; brain injury ... See more keywords
The lncRNA ROR/miR-124-3p/TRAF6 axis regulated the ischaemia reperfusion injury-induced inflammatory response in human cardiac myocytes
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Bioenergetics and Biomembranes"
DOI: 10.1007/s10863-019-09812-9
Abstract: Myocardial ischaemia reperfusion injury (MIRI) is considered the primary cause of death in patients with cardiovascular diseases. Recently, long non-coding RNAs (lncRNAs) and microRNAs (miRNAs) have been found to be involved in the pathogenesis of… read more here.
Keywords: lncrna ror; traf6; ror; cell apoptosis ... See more keywords
The clinical significance of miR-335, miR-124, miR-218 and miR-484 downregulation in gastric cancer
Sign Up to like & getrecommendations! Published in 2018 at "Molecular Biology Reports"
DOI: 10.1007/s11033-018-4278-5
Abstract: Gastric cancer (GC) is one of the leading types of malignancy worldwide, particularly in Asian populations. Although the exact molecular mechanism of GC development remains unknown, microRNA (miRNA) has recently been shown to be involved.… read more here.
Keywords: mir 218; mir; 124 mir; downregulation ... See more keywords
Reduced hsa-miR-124-3p levels are associated with the poor survival of patients with hepatocellular carcinoma
Sign Up to like & getrecommendations! Published in 2018 at "Molecular Biology Reports"
DOI: 10.1007/s11033-018-4431-1
Abstract: Hsa-MicroRNA-124a-3p (hsa-miR-124-3p) is involved in tumor progression in certain malignant tumors. However, its function and clinical implication in hepatocellular carcinoma (HCC) have not yet been illustrated. In this study, we explored the expression and prognostic… read more here.
Keywords: hsa mir; expression; hcc; mir 124 ... See more keywords
The potential role of miR-124-3p in tumorigenesis and other related diseases.
Sign Up to like & getrecommendations! Published in 2021 at "Molecular biology reports"
DOI: 10.1007/s11033-021-06347-4
Abstract: MicroRNAs (miRNAs) are a class of single-stranded noncoding and endogenous RNA molecules with a length of 18-25 nucleotides. Previous work has shown that miR-124-3p leads to malignant progression of cancer including cell apoptosis, migration, invasion,… read more here.
Keywords: tumorigenesis; potential role; role mir; cancer ... See more keywords