Downregulated miR-1247-5p associates with poor prognosis and facilitates tumor cell growth via DVL1/Wnt/β-catenin signaling in breast cancer.
Sign Up to like & getrecommendations! Published in 2018 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2018.09.103
Abstract: The abnormal expression of microRNAs is a key hallmark of breast cancer. Nevertheless, the biological roles of miR-1247-5p in breast cancer remain unknown. In this study, we revealed that miR-1247-5p expression was markedly decreased in… read more here.
Keywords: poor prognosis; breast cancer; mir 1247; dvl1 ... See more keywords
miR-1247 blocks SOX9-mediated regeneration in alcohol- and fibrosis-associated acute kidney injury in mice.
Sign Up to like & getrecommendations! Published in 2017 at "Toxicology"
DOI: 10.1016/j.tox.2017.03.004
Abstract: Excessive alcohol consumption has a significant impact on human health and is a major public health problem worldwide. One of the consequences of long-term excessive alcohol consumption is cellular injury in almost all organs and… read more here.
Keywords: kidney injury; fibrosis; mir 1247; acute kidney ... See more keywords
High circulating miR-1247 is a marker for poor prognosis in patients with metastatic colorectal cancer treated with chemotherapy and cetuximab
Sign Up to like & getrecommendations! Published in 2019 at "Annals of Oncology"
DOI: 10.1093/annonc/mdz246.101
Abstract: Abstract Background MicroRNAs (miRs) are small non-coding RNAs. Circulating miRs in plasma are deregulated in patients with metastatic colorectal cancer (mCRC). The aim was to find prognostic circulating miRs for overall survival (OS) in patients… read more here.
Keywords: mir; colorectal cancer; cetuximab; mir 1247 ... See more keywords
MicroRNA-1247 inhibits cell proliferation by directly targeting ZNF346 in childhood neuroblastoma
Sign Up to like & getrecommendations! Published in 2018 at "Biological Research"
DOI: 10.1186/s40659-018-0162-y
Abstract: BackgroundNeuroblastoma (NB) represents the most common extracranial solid tumor in children. Accumulating evidence shows that microRNAs (miRs) play an important role in the carcinogenesis of NB. Here, we investigated the biological function of miR-1247 in… read more here.
Keywords: microrna 1247; cell proliferation; znf346; mir 1247 ... See more keywords
Knockdown of circRNA circEBF1 inhibits cutaneous squamous cell carcinoma progression by regulating the miR-1247-5p/CSF3 axis.
Sign Up to like & getrecommendations! Published in 2022 at "Histology and histopathology"
DOI: 10.14670/hh-18-468
Abstract: BACKGROUND Cutaneous squamous cell carcinoma (CSCC) is one of the causes of cancer-related death worldwide. Circular RNAs (circRNAs) play a vital role in the pathological process of many malignant tumors. This study aimed to explore… read more here.
Keywords: mir 1247; cell; cscc; csf3 ... See more keywords
Characterization of Adrenal miRNA-Based Dysregulations in Cushing’s Syndrome
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23147676
Abstract: MiRNAs are important epigenetic players with tissue- and disease-specific effects. In this study, our aim was to investigate the putative differential expression of miRNAs in adrenal tissues from different forms of Cushing’s syndrome (CS). For… read more here.
Keywords: mir 1247; mir 379; adrenal mirna; expression ... See more keywords