Genetic variations in miR‐125 family and the survival of non‐small cell lung cancer in Chinese population
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DOI: 10.1002/cam4.2073
Abstract: To investigate the associations between the functional single nucleotide polymorphisms (SNPs) in the miR‐125 family and the survival of non‐small cell lung cancer (NSCLC) patients, we systematically selected six functional SNPs located in three pre‐miRNAs… read more here.
Keywords: mir 125; 125 family; lung cancer; cell ... See more keywords
MicroRNA (miR) 125b regulates cell growth and invasion in pediatric low grade glioma
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DOI: 10.1038/s41598-018-30942-4
Abstract: Members of the miR-125 family are strongly expressed in several tissues, particularly brain, but may be dysregulated in cancer including adult and pediatric glioma. In this study, miR-125 members were downregulated in pilocytic astrocytoma (PA)… read more here.
Keywords: glioma; mir 125; grade; mir 125b ... See more keywords
miR-125 regulates PI3K/Akt/mTOR signaling pathway in rheumatoid arthritis rats via PARP2
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DOI: 10.1042/bsr20180890
Abstract: The present study aimed to explore miR-125 effects on rheumatoid arthritis (RA) development to provide a potential target for RA. Briefly, rat RA model was established (Model group) by injection of Freund’s Complete Adjuvant into… read more here.
Keywords: parp2; mir 125; pi3k akt; group ... See more keywords
P077 Dysregulated miR-125a promotes joint angiogenesis through enhanced glycolysis
Sign Up to like & getrecommendations! Published in 2019 at "Annals of the Rheumatic Diseases"
DOI: 10.1136/annrheumdis-2018-ewrr2019.66
Abstract: Career situation of first and presenting author Post-doctoral fellow. Introduction Psoriatic arthritis (PsA) is characterised by an early vascular phase essential for pannus growth, immune responses and disease progression. Recently, numerous studies have highlighted the… read more here.
Keywords: expression; mir; mir 125; glycolysis ... See more keywords
MiR-125 inhibited cervical cancer progression by regulating VEGF and PI3K/AKT signaling pathway
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DOI: 10.1186/s12957-020-01881-0
Abstract: Background MiR-125 has been shown to be involved in a variety of cancers, including cervical cancer (CC). Here, our goal was to explore miR-125 functional role and molecular mechanism in cervical cancer development and progression.… read more here.
Keywords: pi3k; mir 125; cervical cancer; progression ... See more keywords
Mitochondrion-Directed Nanoparticles Loaded with a Natural Compound and a microRNA for Promoting Cancer Cell Death via the Modulation of Tumor Metabolism and Mitochondrial Dynamics
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DOI: 10.3390/pharmaceutics12080756
Abstract: Mitochondrial dysfunction may cause cancer and metabolic syndrome. Ellagic acid (abbreviated as E), a phytochemical, possesses anticancer activity. MicroRNA 125 (miR-125) may regulate metabolism. However, E has low aqueous solubility, and miR-125 is unstable in… read more here.
Keywords: mir 125; metabolism; mitochondrion directed; cancer ... See more keywords
miR-125-chinmo pathway regulates dietary restriction-dependent enhancement of lifespan in Drosophila
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DOI: 10.7554/elife.62621
Abstract: Dietary restriction (DR) extends healthy lifespan in diverse species. Age and nutrient-related changes in the abundance of microRNAs (miRNAs) and their processing factors have been linked to organismal longevity. However, the mechanisms by which they… read more here.
Keywords: enhancement lifespan; dietary restriction; lifespan; mir 125 ... See more keywords