miR‐125a‐3p aggravates ox‐LDL‐induced HUVEC injury through BAMBI
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Biochemical and Molecular Toxicology"
DOI: 10.1002/jbt.23198
Abstract: Atherosclerosis (AS) is a chronic inflammatory disease characterized by the formation of atherosclerotic plaque in the intima of arteries. Among the known regulators of atherosclerosis, microRNAs (miRNAs) have been reported to play critical roles in… read more here.
Keywords: huvecs; mir 125a; bambi; 125a aggravates ... See more keywords
miR‐125a suppresses malignancy of multiple myeloma by reducing the deubiquitinase USP5
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.29309
Abstract: miR‐125a is a microRNA that is frequently diminished in various human malignancies. However, the mechanism by which impaired miR‐125a promotes cancer growth remains undefined. In this study, we investigated the role of miR‐125a in the… read more here.
Keywords: cell; mir; multiple myeloma; mir 125a ... See more keywords
LncRNA ANRIL/miR‐125a axis exhibits potential as a biomarker for disease exacerbation, severity, and inflammation in bronchial asthma
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Clinical Laboratory Analysis"
DOI: 10.1002/jcla.23092
Abstract: This study aimed to explore the correlation of lncRNA ANRIL/miR‐125a axis with disease risk, severity, and inflammatory cytokines of bronchial asthma. read more here.
Keywords: lncrna anril; disease; 125a axis; bronchial asthma ... See more keywords
LncRNA MIR4435-2HG functions as a ceRNA against miR-125a-5p and promotes neuroglioma development by upregulating TAZ.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of clinical laboratory analysis"
DOI: 10.1002/jcla.24066
Abstract: BACKGROUND Expression of the TAZ gene is closely related to the prognosis of glioma patients. We hoped to find long noncoding RNAs (lncRNAs) related to TAZ and a new target for glioma treatment. METHODS TAZ-related… read more here.
Keywords: glioma; taz gene; lncrna mir4435; mir4435 2hg ... See more keywords
miR-125a-5p promotes gastric cancer growth and invasion by regulating the Hippo pathway.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of clinical laboratory analysis"
DOI: 10.1002/jcla.24078
Abstract: OBJECTIVE This study was carried out to explore the potential involvement of miR-125a-5p in the oncogenic effects of EphA2, TAZ, and TEAD2 and the activity of the Hippo signaling pathway in gastric cancer progression. METHODS… read more here.
Keywords: epha2 taz; taz tead2; invasion; mir 125a ... See more keywords
PinX1 represses renal cancer angiogenesis via the mir-125a-3p/VEGF signaling pathway
Sign Up to like & getrecommendations! Published in 2019 at "Angiogenesis"
DOI: 10.1007/s10456-019-09675-z
Abstract: PIN2/TRF1-interacting telomerase inhibitor 1 (PinX1) is a tumor suppressor in various tumors. However, the molecular mechanism underlying PinX1’s role in cancer development and progression remains unclear. In this study, we aimed to uncover the new… read more here.
Keywords: angiogenesis; pinx1; expression; molecular mechanism ... See more keywords
Reduced LINC00467 elevates microRNA-125a-3p to suppress cisplatin resistance in non-small cell lung cancer through inhibiting sirtuin 6 and inactivating the ERK1/2 signaling pathway.
Sign Up to like & getrecommendations! Published in 2021 at "Cell biology and toxicology"
DOI: 10.1007/s10565-021-09637-6
Abstract: OBJECTIVE The non-coding RNAs have been identified as potential biomarkers in cancers. This study aimed to investigate the effect of long intergenic non-protein coding RNA 467 (LINC00467)/microRNA (miR-125a-3p)/sirtuin 6 (SIRT6) axis on non-small cell lung… read more here.
Keywords: sirt6; signaling pathway; resistance; mir 125a ... See more keywords
MicroRNA-125a-3p overexpression promotes liver regeneration through targeting proline-rich acidic protein 1.
Sign Up to like & getrecommendations! Published in 2019 at "Annals of hepatology"
DOI: 10.1016/j.aohep.2019.05.010
Abstract: INTRODUCTION AND AIM Liver regeneration plays a valuable significance for hepatectomies, and is mainly attributed to hepatocyte proliferation. MicroRNA-125a-3p was reported to be highly associated with liver regeneration process. We studied the underlying mechanism of… read more here.
Keywords: protein; liver regeneration; mir 125a; cell ... See more keywords
Dysregulated miR-125a promotes angiogenesis through enhanced glycolysis
Sign Up to like & getrecommendations! Published in 2019 at "EBioMedicine"
DOI: 10.1016/j.ebiom.2019.08.043
Abstract: Background Although neoangiogenesis is a hallmark of chronic inflammatory diseases such as inflammatory arthritis and many cancers, therapeutic agents targeting the vasculature remain elusive. Here we identified miR-125a as an important regulator of angiogenesis. Methods… read more here.
Keywords: glycolysis; crispr cas9; mir; 125a promotes ... See more keywords
Triptolide ameliorates lupus via the induction of miR-125a-5p mediating Treg upregulation.
Sign Up to like & getrecommendations! Published in 2019 at "International immunopharmacology"
DOI: 10.1016/j.intimp.2019.02.047
Abstract: Triptolide is a biologically active component of the Chinese antirheumatic herbal remedy Tripterygium wilfordii Hook F, which has been shown to be effective in treating murine lupus. However, its immunological mechanisms are poorly understood. Regulatory… read more here.
Keywords: triptolide; effect; 125a expression; mir 125a ... See more keywords
MicroRNA-125a suppresses intestinal mucosal inflammation through targeting ETS-1 in patients with inflammatory bowel diseases.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of autoimmunity"
DOI: 10.1016/j.jaut.2019.04.014
Abstract: MicroRNA (miR)-125a is highly expressed in T cells and regulates the functions of Treg through the IL-6-STAT3 signaling pathway. However, the role of miR-125a in regulating immune responses in intestinal mucosa of patients with inflammatory… read more here.
Keywords: patients inflammatory; inflammatory bowel; intestinal mucosa; bowel diseases ... See more keywords