Development of a Non‐Coding‐RNA‐based EMT/CSC Inhibitory Nanomedicine for In Vivo Treatment and Monitoring of HCC
Sign Up to like & getrecommendations! Published in 2019 at "Advanced Science"
DOI: 10.1002/advs.201801885
Abstract: Abstract The objective of this study is to improve the overall prognosis of patients with hepatocellular carcinoma (HCC); therefore, new therapeutic methods that can be used in vivo are urgently needed. In this study, the… read more here.
Keywords: hcc; vivo; mir 125b; treatment ... See more keywords
MiR‐125b suppresses the carcinogenesis of osteosarcoma cells via the MAPK‐STAT3 pathway
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.27568
Abstract: The microRNA (miRNA) miR‐125b is abnormally expressed in many different types of tumors, including osteosarcoma (OS). How aberrantly expressed miR‐125b participates in regulating the initiation and progression of OS is still poorly understood. In the… read more here.
Keywords: mir 125b; osteosarcoma; stat3; mkk7 ... See more keywords
Long non‐coding RNA MALAT1 promotes oral squamous cell carcinoma development via microRNA‐125b/STAT3 axis
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.26185
Abstract: Oral squamous cell carcinoma (OSCC), as the most common type of oral cancer, is responsible for almost 3% of all malignant tumors worldwide. Non‐coding RNAs such as lncRNAs and microRNAs have been involved in many… read more here.
Keywords: mir 125b; oral squamous; malat1; cell ... See more keywords
Differential expression of microRNAs let‐7a, miR‐125b, miR‐100, and miR‐21 and interaction with NF‐kB pathway genes in periodontitis pathogenesis
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.26391
Abstract: Periodontitis is a chronic inflammatory disease which is caused by destruction of the tissues that surrounds and supports the tooth. Deregulation of microRNAs has been reported to cause several inflammatory diseases such as autoimmune disease,… read more here.
Keywords: mir 125b; expression; let mir; mir 100 ... See more keywords
Upregulation of endothelial cell-derived exosomal microRNA-125b-5p protects from sepsis-induced acute lung injury by inhibiting topoisomerase II alpha
Sign Up to like & getrecommendations! Published in 2021 at "Inflammation Research"
DOI: 10.1007/s00011-020-01415-0
Abstract: Objective Emerging evidence has revealed that exosomal microRNAs (miRNAs) are implicated in human diseases. However, role of exosomal miR-125b-5p in sepsis-induced acute lung injury (ALI) remains further explored. We focused on the effect of exosomal… read more here.
Keywords: mir 125b; lung; top2a; cell ... See more keywords
Increased plasma levels of miR-124-3p, miR-125b-5p and miR-192-5p are associated with outcomes in acute ischaemic stroke patients receiving thrombolysis.
Sign Up to like & getrecommendations! Published in 2019 at "Atherosclerosis"
DOI: 10.1016/j.atherosclerosis.2019.08.002
Abstract: BACKGROUND AND AIMS Circulating microRNAs (miRNAs) have recently emerged as promising biomarkers for acute ischaemic stroke (AIS). However, the expression profiles of miRNAs in AIS patients receiving intravenous thrombolysis, and their associations with outcome have… read more here.
Keywords: mir 125b; mir; thrombolysis; patients receiving ... See more keywords
Silencing LncRNA-DANCR attenuates inflammation and DSS-induced endothelial injury through miR-125b-5p.
Sign Up to like & getrecommendations! Published in 2020 at "Gastroenterologia y hepatologia"
DOI: 10.1016/j.gastrohep.2020.10.008
Abstract: BACKGROUND LncRNA-DANCR is involved in inflammation and acts as a major contributor to colon cancer. The effects and mechanism of LncRNA-DANCR were first investigated in a DSS-induced colitis model in vivo and vitro. MATERIAL AND… read more here.
Keywords: mir 125b; dss induced; inflammation; lncrna dancr ... See more keywords
Identification of a miRNAs signature associated with exposure to stress early in life and enhanced vulnerability for schizophrenia: New insights for the key role of miR-125b-1-3p in neurodevelopmental processes
Sign Up to like & getrecommendations! Published in 2019 at "Schizophrenia Research"
DOI: 10.1016/j.schres.2018.07.030
Abstract: Epidemiological and clinical studies have provided evidence for a role of both genetic and environmental factors, such as stressful experiences early in life, in the pathogenesis of Schizophrenia (SZ) and microRNAs (miRNAs) have been suggested… read more here.
Keywords: mir 125b; stress; early life; key role ... See more keywords
DNA functionalized double quantum dots-based fluorescence biosensor for one-step simultaneous detection of multiple microRNAs.
Sign Up to like & getrecommendations! Published in 2021 at "Talanta"
DOI: 10.1016/j.talanta.2021.122763
Abstract: The disease diagnosis by detecting single microRNAs (miRNAs) can produce high false positive rate. Herein, a novel fluorescence biosensor method for one-step simultaneous detection of multiple miRNAs was proposed by using single-stranded DNA (ssDNA) functionalized… read more here.
Keywords: detection; fluorescence biosensor; fluorescence; mir 125b ... See more keywords
Interaction of miR-125b-5p with Human antigen R mRNA: Mechanism of controlling HCV replication.
Sign Up to like & getrecommendations! Published in 2018 at "Virus research"
DOI: 10.1016/j.virusres.2018.09.006
Abstract: Cellular miRNAs influence Hepatitis C virus (HCV) infection in multiple ways. In this study, we demonstrate that miR-125b-5p is upregulated in HCV infected patient serum samples as well as in HCV infected liver carcinoma cells… read more here.
Keywords: hcv replication; mir 125b; hur; human antigen ... See more keywords
MicroRNA (miR) 125b regulates cell growth and invasion in pediatric low grade glioma
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DOI: 10.1038/s41598-018-30942-4
Abstract: Members of the miR-125 family are strongly expressed in several tissues, particularly brain, but may be dysregulated in cancer including adult and pediatric glioma. In this study, miR-125 members were downregulated in pilocytic astrocytoma (PA)… read more here.
Keywords: glioma; mir 125; grade; mir 125b ... See more keywords